Design and Analysis of Biomolecular Circuits : Engineering Approaches to Systems and Synthetic Biology

Heinz Koeppl

ISBN 10: 1441967656 / ISBN 13: 9781441967657

Editore: Springer New York, 2011

Riguardo questo articolo

Druck auf Anfrage Neuware - Printed after ordering - The book deals with engineering aspects of the two emerging and intertwined fields of synthetic and systems biology. Both fields hold promise to revolutionize the way molecular biology research is done, the way today's drug discovery works and the way bio-engineering is done. Both fields stress the importance of building and characterizing small bio-molecular networks in order to synthesize incrementally and understand large complex networks inside living cells. Reminiscent of computer-aided design (CAD) of electronic circuits, abstraction is believed to be the key concept to achieve this goal. It allows hiding the overwhelming complexity of cellular processes by encapsulating network parts into abstract modules. This book provides a unique perspective on how concepts and methods from CAD of electronic circuits can be leveraged to overcome complexity barrier perceived in synthetic and systems biology.

Codice articolo 9781441967657

Dati bibliografici

• Titolo: Design and Analysis of Biomolecular Circuits : Engineering Approaches to Systems and Synthetic Biology
• Editore: Springer New York
• Data di pubblicazione: 2011
• Lingua: Inglese
• ISBN 10: 1441967656
• ISBN 13: 9781441967657
• Rilegatura: Buch
• Condizione: Neu
• Dimensioni: 243 L x 167 A x 29 P (millimetri) 243 millimetri di larghezza per 167 millimetri di altezza per 29 millimetri di profondità
• Peso: 742 grammi

Descrizione articolo

Riassunto

The book deals with engineering aspects of the two emerging and intertwined fields of synthetic and systems biology. Both fields hold promise to revolutionize the way molecular biology research is done, the way today s drug discovery works and the way bio-engineering is done. Both fields stress the importance of building and characterizing small bio-molecular networks in order to synthesize incrementally and understand large complex networks inside living cells. Reminiscent of computer-aided design (CAD) of electronic circuits, abstraction is believed to be the key concept to achieve this goal. It allows hiding the overwhelming complexity of cellular processes by encapsulating network parts into abstract modules. This book provides a unique perspective on how concepts and methods from CAD of electronic circuits can be leveraged to overcome complexity barrier perceived in synthetic and systems biology.

Dalla quarta di copertina

This book is devoted to the design and analysis of biomolecular circuits as considered in systems biology and synthetic biology. The aim of the book is to present in a coherent framework some of the most recent work on the analysis, simulation and design of biomolecular circuits and systems, reflecting the interdisciplinary and collaborative nature of the field. The results discussed range from how these systems should be modeled and analyzed, to how they should be physically designed and implemented.

Drawing parallels to electronic circuit design, this book s contents are organized to reflect what the editors believe are the important, necessary steps to build complex synthetic circuits. Coverage includes analysis and simulation, modularity and abstraction, design and standardization, and enabling technologies. Each of these themes is organized in different chapters that are self-contained so that they can be read individually by experts but also read sequentially by someone wanting to get an overview of the field. This book is intended for computational scientists, e.g. mathematicians, physicists, computer scientist or engineers as well as for researchers from the life sciences. Every effort has been made to make the presentation accessible to a broad, multi-disciplinary audience.