Hardcover. This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include -spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials. Sequential Clinical Trials are those where data from patients treated at the beginning of a trial can be analysed while the trial is on-gong and subsequent patients are recruited. This analysis provides stopping rule whereby the number of patients involved can be limited without affecting the results. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.

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Dati bibliografici

Titolo: The Design and Analysis of Sequential Clinical Trials (Hardcover)
Editore: John Wiley & Sons Inc, New York
Data di pubblicazione: 1997
Lingua: Inglese
ISBN 10: 0471975508
ISBN 13: 9780471975502
Rilegatura: Hardcover
Edizione: seconda edizione
Condizione: new

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Riassunto

Alles �ber Planung, Durchf�hrung und Analyse sequentieller klinischer Versuche - das sind Versuche, bei denen erste Daten von Patienten bereits ausgewertet werden k�nnen, w�hrend der Versuch mit neuen Testpersonen fortgef�hrt wird. Die �berarbeitete Neuauflage bezieht sich unter anderem auf die Software PEST (Planning and Education of Sequential Trials).

Informazioni sull?autore

John Whitehead is the author of The Design and Analysis of Sequential Clinical Trials, Revised, 2nd Edition, published by Wiley.

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