Development of Directly Compressible Co-processed Excipients : Strategies for Development of Directly compressible Co-processed Excipients Used in Tablet

Sanjay Patel

ISBN 10: 3844398392 / ISBN 13: 9783844398397

Editore: LAP LAMBERT Academic Publishing, 2011

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nach der Bestellung gedruckt Neuware - Printed after ordering - Direct compression method in tableting is widely used due to fewer processing steps, simplified validation, elimination of heat and moisture, economy and improved drug stability. Hence, the current trend in the pharmaceutical industry is to adopt direct compression technology. Most of the drugs do not possess direct compression characteristic. Hence, development of various functionality added excipients (FAEs) to achieve formulations with desired effects is equally important. Excipients with improved functionality can be obtained by developing new chemical excipients, new grades of existing materials and new combination of existing materials. A much broader platform for the manipulation of excipient functionality is provided by co-processing or particle engineering of two or more excipients. The most important approach for controlling price for the excipients is to develop co-processed directly compressible excipients.

Codice articolo 9783844398397

Dati bibliografici

• Titolo: Development of Directly Compressible Co-processed Excipients : Strategies for Development of Directly compressible Co-processed Excipients Used in Tablet
• Editore: LAP LAMBERT Academic Publishing
• Data di pubblicazione: 2011
• Lingua: Inglese
• ISBN 10: 3844398392
• ISBN 13: 9783844398397
• Rilegatura: Taschenbuch
• Condizione: Neu
• Dimensioni: 220 L x 150 A x 13 P (millimetri) 220 millimetri di larghezza per 150 millimetri di altezza per 13 millimetri di profondità
• Peso: 328 grammi

Descrizione articolo

Riassunto

Direct compression method in tableting is widely used due to fewer processing steps, simplified validation, elimination of heat and moisture, economy and improved drug stability. Hence, the current trend in the pharmaceutical industry is to adopt direct compression technology. Most of the drugs do not possess direct compression characteristic. Hence, development of various functionality added excipients (FAEs) to achieve formulations with desired effects is equally important. Excipients with improved functionality can be obtained by developing new chemical excipients, new grades of existing materials and new combination of existing materials. A much broader platform for the manipulation of excipient functionality is provided by co-processing or particle engineering of two or more excipients. The most important approach for controlling price for the excipients is to develop co-processed directly compressible excipients.

L'autore

Dr. Sanjay S. Patel, (Associate Professor, Pharmaceutics Department) and Dr. Natvarlal M. Patel (Principal) working in Shri B. M. Shah College of Pharmaceutical Education and Research, Modasa – 383315, India