Environmental Effects on Molecular Structure and Properties: Proceedings of the Eighth Jerusalem Symposium on Quantum Chemistry and Biochemistry Held in Jerusalem, April 7th-11th 1975

The holding of the 8th Jerusalem Symposium was saddened by the sudden death of Professor Ernst D. Bergmann at the very eve of this meeting. With him disappeared one of the leading world scientists in the field of physical chemistry and biochemistry. His innumerable friends and admirers over the whole world mourn him profoundly. All those who knew him personally and among them the participants in the previous Jerusalem Symposia will remember for ever the exceptional qualities of the scientist and the unusual human warmth of the man. With Ernst D. Bergmann the state of Israel lost one of the founders of its Science and one of its most brilliant and renowned representatives. The spirit which he suc­ ceeded to inoculate into his numerous disciples and pupils will, however, continue to perpetuate his name and his work. The Jerusalem Symposia will continue as a living testimony to his brilliant inspiration. Before dying, Professor Bergmann has prepared a few opening remarks for the 8th Jerusalem Symposium. They are reproduced here. BERNARD PULLMAN OPENING WORDS Prepared by the Late Professor Ernst David Bergmann It gives me great pleasure to welcome you all on behalf of the President and the Rector of the Hebrew University which is co-sponsoring this meeting, and of the President and Council of the Israel Academy of Sciences and Humanities which for the eighth time has put its premises at our disposal.

Molecular Orbital ‘Supermolecule’ Approach to the Solvation Problem.- On the Development of Solvent Effect Models: Method Development and Initial Applications.- Electrostatic Properties of Proteins: Role of the Aqueous Solution in Determining Protein Secondary and Tertiary Structure.- Approaches to the Problem of Solvation Calculations in Polar and Charged Molecules.- Quantum-Mechanical Studies on the Effect of Water on the Conformation of Two Biologically Important Zwitterionic Systems: Polar Head of Phospholipids and GABA.- Solvent Effects on Acidity and Basicity from Gas Phase Ion Equilibria Measurements.- Conformation of Peptides in Water.- Theoretical Studies on the Conformation of Peptides in Solution. II: Conformations of N-Acetyl L-Alanine N-Methyl Amide in CCl4 and H2O and N-Acetyl Glycine N-Methyl Amide in CCl4.- Molecular Environmental Effects on the Puckering of the Proline Ring.- Molecular Design: Theoretical and Solution Studies on Copper(II) Complex of Glycylglycyl-L-Histidine-N-Methyl Amide, a Peptide Designed to Mimic the Copper(II)-Transport Site of Human Albumin.- Molecular Complexes and Chemical Behaviour: Competitive Preferential Solvation Theory and its Applications.- Calorimetric Studies of Hydrophobic Interactions in Aqueous Solution.- Changes in the Adherence of Hydrophobic Groups, and Corresponding Alterations in Molecular Conformation of Biopolymers, with Changes in Interfacial Tension of their Aqueous Solutions.- Solute-Solute and Solute-Solvent Interactions: NMR Studies.- Theoretical Study of the Solvent Effect on Ionization and Partition Behavior in Related Opiate Narcotics: Hydromorphone and Oxymorphone.- Solvent Effect and Aromatic Compounds: Magneto-Optic Properties.- ?-Cyclodextrin Inclusion Complexes: Mechanism of Adduct Formation and Intermolecular Interactions.- Correlation of Chemical Reactivity in the Solid State with Crystal Structure.- The Effects of the Crystal Lattice on the Electronic Distribution of the Nitrite Ion in the Ferroelectric Phase of Na2NO2.- Intra- and Intermolecular Interactions in Azanucleosides.- Chromophore Protein Interactions in Visual Pigments and their Analogs.- Effect of the Counter Anion on the Oxidation of N-Benzyl-1, 4-Dihydronicotinamide.- Influence of Cations on Secondary Structures of Macromolecules and Membranes - IR Investigations.- Hemoglobin Interaction in Sickle Cell Fibers: Theoretical Approaches to the Molecular Contacts.- Application of Competitive Labeling to the Study of the Effect of Environment on the Chemical Properties of Groups in Proteins: Environmental Effects on Histidine Residues.- The Stability of Bovine Pancreatic Ribonuclease in Glycerol and Glycerol-Cosolvents.- A New Empirical Intermolecular Potential Energy Function for Hydrogen Bonding: Application to the Gas Phase and Solid State of Carboxylic Acids and Alcohols.- Use of Energy Calculations to Refine and Understand Structure and Function of Proteins.- Coenzyme Apoenzyme Interactions: Studies on the Binding of Thiamine Diphosphate to Apotransketolase from Baker’s Yeast.- Electron Transport in Cytochrome C.- The Effect of Temperature on the Structure of Lysozyme in Solution.- On the Anesthetic Potency of Fluorocarbons, Their Ionization Potentials, and Their Dissociative Effect on Hydrogen Bonds.- A Preliminary Refinement of Yeast tRNAPhe at 3 Å Resolution.- The Modification by Biliproteins of Intensity and Direction of Electron Flow across Chlorophyll-Containing Membranes.- Environmental Effects on Processes of Excited Molecules - External Spinorbit Coupling Effects on Photochemical Reactions of Bianthrone-like Molecules.- Ground-State versus Excited-State Polarity of Triafulvenes: A Study of Solvent Effects on Molecular Electronic Spectra.- Index of Names.