Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders presents a state-of-the-art review of the effects of environmental contaminants on the development and degeneration of the human nervous system, brought together by world-leading experts in the field.
Part One describes the adverse effects that the environment can have on neurological development, and how these effects may exhibit. Specific contaminants and their possible consequences of exposure are addressed (lead, methylmercury, alcohol), as well as specific disorders and the environmental factors associated with them, such as the effect of diet on attention deficit and hyperactivity disorders. Part Two tackles neurodegenerative disorders, specifically addressing their potential neurotoxic origins, and discussing the increasing interest in the effects that early exposure may have in later life.
Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders is an invaluable reference for those professionals working in the fields of toxicology, environmental health and neuroscience.
- Provides, for the first time, the cutting-edge theory of environmental impacts on both neurodegenerative and neurodevelopmental disorders
- Written by an international selection of the world’s foremost experts in the field of neurotoxicology
- Full-colour throughout, providing accurate and illustrative examples of neurotoxic effects in action
- An invaluable reference for those professionals working in the fields of toxicology, environmental health, and neuroscience
Dr. Aschner earned his B.S. from the University of Rochester and Ph.D. in Anatomy and Neurobiology from the University of Rochester School of Medicine and Dentistry, Rochester, NY. He presently serves as the Harold and Muriel Block Chair in Molecular Pharmacology; Professor of Molecular Pharmacology and Neuroscience and Senior Scientist at Kennedy Center, Albert Einstein College of Medicine, Bronx, NY. Dr. Aschner served on numerous national and international toxicology panels (Institute of Medicine, US Environmental Protection Agency, Center for Disease Control, Neurotoxicology and Alcohol (NAL) National Institutes of Health Study Section). He is a Fellow of the Academy of Toxicological Sciences and a past president of the International Neurotoxicology Association. In 2011, he received the Society of Toxicology Merit Award. His research interests are in the neurobiology and physiology of astrocytes and mechanisms of central nervous system injury, with emphasis on metal uptake and distribution. His research focuses on transport of methylmercury, manganese and uranium across the blood-brain barrier, and their cellular and molecular mechanisms of neurotoxicity. Dr. Lucio G. Costa is Professor of Toxicology at the University of Washington in Seattle. He received a doctorate in Pharmacology from the University of Milano in 1977, and was a postdoctoral fellow at the University of Texas at Houston, before joining the Faculty at the University of Washington in 1983. He is also the Director of the Neurotoxicology Research Core of the NIEHS Center in Ecogenetics and Environmental Health, and a Core Faculty of the Environmental and Occupational Epidemiology Training Program and the Environmental Pathology/Toxicology Training Program at the University of Washington. From 1991 to 2000 he served as the Director of the University of Washington Toxicology Program. He has also held professorial positions at various Universities in Italy (Parma, Bari, Roma, Pavia, Milano). He is a member of several national and international professional organizations, a Fellow of the Academy of Toxicological Sciences, and a European Certified Toxicologist. He received various award for his scientific accomplishments, including the Achievement Award from the Society of Toxicology. He serves in various editorial capacities for several toxicology journals, and is an active manuscript and grant reviewer. Dr. Costa has been the member of several panels and committees at the national and international level dealing with toxicology and risk assessment issues. He has chaired and/or organized symposia at dozens of scientific meetings in the United States and internationally. He has been teaching classes in the area of pharmacology, toxicology, and neurotoxicology for over 30 years, and has kept an active research program in the area of neurotoxicology, with over 380 publications, books and book chapters.
