Enzyme Chemistry : Impact and applications

Colin J. Suckling

ISBN 10: 9401089574 / ISBN 13: 9789401089579

Editore: Springer Netherlands, 2012

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Druck auf Anfrage Neuware - Printed after ordering - In the molecular sciences, enzyme chemistry occupies a special niche as one of the major contact points between chemical and biological disciplines. The special properties of enzymes as selective and efficient catalysts are so central to current challenges to chemists that the development of enzyme chemistry in the past thirty years has been a major stimulus to chemical research in general. On the one hand studies of the intrinsic properties of enzymes and, on the other hand, their applications to synthesis, drug design, and biosynthesis have had an immense impact. This book brings together in one volume essays describing several such fields with emphasis on the applications. It would be unnecessarily repetitious to outline the approach and contents of the book in a Preface; the first short chapter is more eloquent than a formal Preface can be. I shall therefore encourage you to begin with the Introduction in Chapter 1 and here I wish to extend my warm thanks to those who have contributed to the production of this book: the authors for their acceptance of the overall concept of the book and for the thoughtfulness of their writing; Dr Charles Suckling, FRS and Professor Hamish Wood for their constructive criticism of the whole book; and Dr John Buckingham and his colleagues at Chapman and Hall for their efficiency and enthusiasm in transforming the typescripts into the book that you now hold. Colin J. Suckling University of Strathclyde Contributors Donald H.

Codice articolo 9789401089579

Dati bibliografici

• Titolo: Enzyme Chemistry : Impact and applications
• Editore: Springer Netherlands
• Data di pubblicazione: 2012
• Lingua: Inglese
• ISBN 10: 9401089574
• ISBN 13: 9789401089579
• Rilegatura: Taschenbuch
• Condizione: Neu

Descrizione articolo

Riassunto

In the molecular sciences, enzyme chemistry occupies a special niche as one of the major contact points between chemical and biological disciplines. The special properties of enzymes as selective and efficient catalysts are so central to current challenges to chemists that the development of enzyme chemistry in the past thirty years has been a major stimulus to chemical research in general. On the one hand studies of the intrinsic properties of enzymes and, on the other hand, their applications to synthesis, drug design, and biosynthesis have had an immense impact. This book brings together in one volume essays describing several such fields with emphasis on the applications. It would be unnecessarily repetitious to outline the approach and contents of the book in a Preface; the first short chapter is more eloquent than a formal Preface can be. I shall therefore encourage you to begin with the Introduction in Chapter 1 and here I wish to extend my warm thanks to those who have contributed to the production of this book: the authors for their acceptance of the overall concept of the book and for the thoughtfulness of their writing; Dr Charles Suckling, FRS and Professor Hamish Wood for their constructive criticism of the whole book; and Dr John Buckingham and his colleagues at Chapman and Hall for their efficiency and enthusiasm in transforming the typescripts into the book that you now hold. Colin J. Suckling University of Strathclyde Contributors Donald H.

Contenuti

1. Infant enzyme chemistry.- 2. The mechanistic basis of enzyme catalysis.- 3. Chemical models of coenzyme catalyses.- 4. Selectivity in synthesis — chemicals or enzymes.- 5. Enzymes as targets for drug design.- 6. Metal ions in biological systems.- 7. Enzyme-level studies of the biosynthesis of natural products.- 8. The impact of enzymology in biochemistry and beyond.