Extracellular Matrix in Development

Douglas W. Desimone (u. a.)

ISBN 10: 3642359345 / ISBN 13: 9783642359347

Editore: Springer, 2013

Extracellular Matrix in Development | Douglas W. Desimone (u. a.) | Buch | x | Englisch | 2013 | Springer | EAN 9783642359347 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. Codice articolo 106050706

Riassunto:

Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.

Dalla quarta di copertina:

Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.

The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.

Dati bibliografici

Titolo: Extracellular Matrix in Development
Casa editrice: Springer
Data di pubblicazione: 2013
Legatura: Buch
Condizione: Neu