FOUNDATIONS OF CARDIAC ARRHYTHMIAS : BASIC CONCEPTS AND CLINICAL APPROACHES

ISBN 10: 0824702662 / ISBN 13: 9780824702663

Editore: CRC Press, 2000

Brand New Original US Edition. Customer service! Satisfaction Guaranteed. Codice articolo ASNNN-77857

Riassunto:

This single-source reference/text is an authoritative, up-to-date, and multidisciplinary presentation of basic, applied, and clinical approaches to the diagnosis, treatment, and management of cardiac arrhythmia and the prevention of sudden cardiac death-providing essential concepts for new approaches to pharmacologic and electrical therapies.

Over 50 leading physicians, scientists, and engineers integrate their research knowledge into a solid foundation of fundamentals in innovative new ways to promote an understanding of cardiac arrhythmias on a multilevel basis that spans the full range of topics from genes to therapy prevention.

From the regular rhythm of the heart to the irregular, chaotic states that characterize fibrillation and tachyarrhythmias, Foundations of Cardiac Arrhythmias

explores the ionic and molecular basis of electrogenesis and its control within different types of cardiac cells

clarifies the molecular and biochemical regulation of cell-to-cell conduction that will help facilitate development of the next generation of antiarrhythmic drugs

considers genetic determinants that influence the onset of sudden death in rare and acquired heart disease

explores recent insights into macroscopic, three-dimensional interactions implicated in the genesis of malignant ventricular tachycardias

surveys population studies that reveal new information about the relevance of higher frequency polymorphisms and variations in molecules involved in cardiac control

discusses the role of cardiac ablation and the use of pacemakers and defibrillators, including new concepts in device design

discusses promising new advances with noninvasive markers of arrhythmia risk that are helping to identify patients at risk for sudden death
Containing nearly 2300 key literature citations and over 300 helpful drawings, photographs, equations, and tables, Foundations of Cardiac Arrhythmias serves as a thorough and inspiring reference for clinical and research cardiologists, clinical and basic electrophysiologists, pharmacologists, molecular and cell physiologists, biologists, biochemists, molecular geneticists, biomedical and electrical engineers, and biophysicists, as well as an important text for graduate students, residents, and fellows in these disciplines.

Contenuti: Perspectives on Arrhythmogenesis; Antiarrhythmic Strategies; and Sudden Cardiac Death
Peter M. Spooner and Michael R. Rosen

Ion Channels to Action Potentials

Cardiac Membrane and Action Potentials
Dan M. Roden
Cardiac Ion Channels
Harry A. Fozzard
Cardiac Ion Pumps and Ion Exchangers
Arnold Schwartz and Denis Noble
Regulation of Cardiac Ion Channels and Transporters
H. Criss Hartzell and Arnold M. Katz
Molecular Diversity and Distribution of Cardiac Ion Channels
Harold C. Strauss and Arthur M. Brown

Action Potentials to Tissue Activation

Sinoatrial Node and Impulse Initiation
Richard B. Robinson and Dario DiFrancesco
Intracardiac Cell Communication and Gap Junctions
Jeffrey E. Saffitz and Mark J. Yeager
Impulse Conduction: Continuous and Discontinuous
Charles Antzelevitch and Madison S. Spach
Networks: Fundamental Properties and Models
Ronald W. Joyner and André G Kléber
Atrioventricular Conduction
Ralph Lazzara; Benjamin J. Scherlag; and Luiz Belardinelli
Ca2+ and Arrhythmias
Henk E .D. J. ter Keurs and Penelope A. Boyden

Tissue Activation to Cardiac Rhythm

The Electrocardiogram and Electrophysiological Analysis
David M. Mirvis and Robert Plonsey
Global Behaviors of Cardiac Activation
Yoram Rudy and José Jalife
Mapping and Invasive Analysis
Robert L. Lux; Masood Akhtar; and Robert S. MacLeod

Arrhythmias: Origins and Mechanisms

Automaticity and Triggered Activity
Marc A. Vos and Bruce B. Lerman
Reentry
Michiel J. Janse and Eugene Downar
Atrial Fibrillation
Albert L. Waldo and David R. Van Wagoner
Ventricular Fibrillation and Defibrillation
Stephen M. Dillon and Richard A. Gray
Origins; Classification; and Significance of Ventricular Arrhythmias
Robert J. Myerburg; Heikki V. Huikuri; and Agustin Castellanos

Therapeutic Strategies and Future Directions

Cardiac Pacemakers
Adam Zivin; Rahul Mehra; and Gust H. Bardy
Implantable Cardioverter Defibrillators
Adam Zivin; Rahul Mehra; and Gust H. Bardy
Remodeling: Structural and Electrical Considerations
Gordon F. Tomaselli and Karl T. Weber
Transgenic Electrophysiology and Small Animal Models
Amit Rakhit and Charles I. Berul
Genetic Approaches and Familial Arrhythmias
Jeffrey A. Towbin and Ketty Schwartz
New Directions for Arrhythmic Drug Development Based on Molecular Approaches to Arrhythmogenesis
Eduardo Marbán and Michael Sanguinetti
Ablation Therapy of Cardiac Arrhythmias
Douglas P. Zipes
Risk Identification by Noninvasive Markers of Cardiac Vulnerability
Richard L. Verrier and Richard J. Cohen
Sudden Cardiac Death and Its Prevention
Christine M.. Albert; Leonard A. Cobb; and Jeremy N. Ruskin

Dati bibliografici

Titolo: FOUNDATIONS OF CARDIAC ARRHYTHMIAS : BASIC ...
Casa editrice: CRC Press
Data di pubblicazione: 2000
Legatura: Rilegato
Condizione: New