Floating Technology | focusing on an emerging sublimation method

Pratik Vora

ISBN 10: 3659552267 / ISBN 13: 9783659552267

Editore: LAP LAMBERT Academic Publishing, 2014

Floating Technology | focusing on an emerging sublimation method | Pratik Vora | Taschenbuch | 148 S. | Englisch | 2014 | LAP LAMBERT Academic Publishing | EAN 9783659552267 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Codice articolo 105217336

Riassunto:

Ranitidine Hydrochloride, an Histamine 2 receptor antagonist, can be absorbed in upper part of GIT including stomach and proximal intestine. Moreover, when it comes in contact with colonic media, degradation starts. Low density floating tablets of Ranitidine Hydrochloride were prepared using polyethylene oxide (POLYOX WSR N 60 K) as a polymer and L-Menthol as a sublimating material. Sublimation technique, generally used for mouth dissolving tablet, was used to make porous tablet that have minimal lag time just within a fraction of time and floated for more than 24 h. Moreover, tablet floating lag time was independent of pH of media, which was limitation for conventional floating tablets. Stability data proved that dosage form was also stable for longer period.

L'autore: Mr. Pratik Vora, Master of Pharmacy,Pharmaceutics at Parul Institute of Pharmacy affiliated to Gujarat Technological University, Gujarat, India. He was ranked fourth during bachelor degree by the same university.

Dati bibliografici

Titolo: Floating Technology | focusing on an ...
Casa editrice: LAP LAMBERT Academic Publishing
Data di pubblicazione: 2014
Legatura: Taschenbuch
Condizione: Neu