Food Allergy and Intolerance

The 2nd Edition of FOOD ALLERGY AND INTOLERANCE is the definitive guide to this subject. In the 15 years since the first edition was published, the subject has become the focus of intense public interest. This interest has led to unprecedented growth in the field with new evidence and practices constantly being introduced. This latest edition encompasses the rigor and depth of the first but is updated with the new advances in the field, resulting in 40% entirely new material.

• Includes the scientific basis for the clinical observations
• Describes the underlying mechanisms of the allergic response
• Detailed accounts of all end-organ effects
• Outstanding sections of investigation, diagnosis and treatment

• Incorporates advances in understanding the immune response
• Animal models of sensitivity
• Mediators in food allergy
• Enzyme deficiency
• Abnormal nutrition and immune response to foods
• Food-induced migraine and epilepsy
• Hyperactivity: ADHD
• The psychological aspects of food intolerance

Part I: Basic Mechanisms
Section A: Normal Structure and Function
1. The structure and organization of lymphoid tissue in the gut
2. Basic function of the gut
3. Adhesion molecules and circulation and differentiation of lymphocytes in GALT and mammary glands
4. Innervation of mucosal lymphoid tissue and effect of neuropeptides release
Section B: Specialized Cells and Secretions of the Gut
5. Gut associated macrophages
6. Intestinal mast cells
7. The mucosal T cell and natural killer cells
8. Narural Killer cells and aspects of intestinal immunity
9. The mucosal B cell and its functions
10. Enterocytes
11. Mucosal antibodies and induction of the immunoglobulin A response
12. The composition and function of the mucus barrier in the gastrointestinal tract
Section C: Antigen Handling and Immune Response
13. Role of mucosal barrier in antigen handling by the gut
14. Immunodeficiency and antigen exclusion
15. Causes and consequences of altered gut permeability
16. Oral tolerance: Probable mechanisms and possible therapeutic applications
Section D: Mechanisms of Damage
17. Intestinal Pathogenic correlates of clinical food allergic disorders
18. Animal models of food sensitivity
19. Immunologically medicated damage of the gut
20. Non - immune damage to the gut
21. Mediators in food allergy
22. Diet and the metabolism of intestinal bacteria
23. Infections of the gastrointestinal tract and food tolerance
24. Is there an allergic and fermentive gut condition, and does it relate to Candida
25. Enzyme deficiency

Part II: Food Components and Their Reactions
Section A: Examples of Foods as Allergens
26. Nutritional effects on human immune function
27. Food as allergens
28. Acute Allergic reactions to foods and cross reactivity between foods
29. Fish Allergy and the codfish allergen model
30. Cow' milk and breast milk
Section B: Non-Allergenic Effects of Food
31. Pharmacological actions of food and drink
32. Food chemicals and their elimination
33. Exorphins and other biologically active peptides derived form diet
34. Dietary lections and disease

Part III: End-Organ Effect
Section A: Respiratory Tract
35. Phinitis and secretory otitis media and sinus disease caused by food allergy
36. Food induced asthma
37. Alveolitis
Section B: Gastrointestinal Tract
38. Intestinal manifestation of food allergy and intolerance
39. Oral manifestation of food allergy and intolerance
40. Gluten toxicity in coeliac disease
41. Irritable bowel syndrome, Crohn's disease and ulcerative colitis
42. Pediatric gastrointestinal food-allergic disease
Section C: Skin
43. Atopic eczema
44. Food intolerance in uticaria and angio - edema and urticuarial Vasculitis
45. Skin contact reactions to foods and spices
46. Dermatitis herpetiformis
Section D: Central Nervous System
47. Effects of food on the central nervous system
48. Psychological aspects of food intolerance
49. Psychologization of illness
50. Food allergy and the central nervous system in childhood
51. The Hyper Kinetic syndrome
52. The Potential role of trace elements in child hyper kinetic disorders
53. Food addiction and criminal behavior
Section E: Rheumatology
54. Joints and connective tissue damage
55. Ankylosing spondylitis and diet
Section G: Other Organs
56. Food sensitivity: The kidney and bladder
57. Cardiovascular disease in response to food and chemical
58. Historical perspectives: clinical presentations, pathogenesis and diagnosis of food hypersensitivities
59. Elimination diets as a diagnostic tool
60. Food allergy/sensitivity diagnosed by skin testing
61. Laboratory diagnosis of food intolerance
62. Diagnosis of gastrointestinal food allergic disease in children
63. Diagnosis of gastrointestinal food allergy and intolerance in adults
64. Non-immunological adverse reactions to food
65. Hyperventilation and allergy
66. Practical application and hazards of dietary management in food intolerance

Part V: Treatment of Food Allergy
67. Drug treatment of food allergy and intolerance
68. The contribution of an environmental unit to the diagnosis and management of chronic symptoms
69. Enzyme - potentated desensitization
70. Prevention of food allergy in infants and children