Frontiers in Molecular Design and Chemical Information Science - Herman Skolnik Award Symposium 2015

Lingua: inglese

Editore: Oxford University Press Inc, US, 2017

0841231419 / 9780841231412

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This book focuses on broadly defined areas of chemical information science- with special emphasis on chemical informatics- and computer-aided molecular design. The computational and cheminformatics methods discussed, and their application to drug discovery, are essential for sustaining a viable drug development pipeline. It is increasingly challenging to identify new chemical entities and the amount of money and time invested in research to develop a new drug hasgreatly increased over the past 50 years. The average time to take a drug from clinical testing to approval is currently 7.2 years. Therefore, the need to develop predictive computational techniques to drive research more efficiently to identify compounds and molecules, which have the greatestlikelihood of being developed into successful drugs for a target, is of great significance. New methods such as high throughput screening (HTS) and techniques for the computational analysis of hits have contributed to improvements in drug discovery efficiency.The SARMs developed by Jürgen and colleagues have enabled display of SAR data in a more transparent scaffold/functional SAR table. There are many tools and databases available for use in applied drug discovery techniques based on polypharmacology. The cheminformatics approaches and methodologies presented in this volume and at the Skolnik Award Symposium will pave the way for improved efficiency in drug discovery. The lectures and the chapters also reflect the various aspects of scientificenquiry and research interests of the 2015 Herman Skolnik award recipient.…

Codice articolo LU-9780841231412

Titolo
Frontiers in Molecular Design and Chemical Information Science - Herman Skolnik Award Symposium 2015
Autore
Rachelle J. Bienstock, Veerabahu Shanmugasundaram, Jürgen Bajorath
Editore
Oxford University Press Inc, US
Anno di pubblicazione
2017
Condizione
New
Rilegatura
Hardback
Lingua
inglese
ISBN 10
0841231419
ISBN 13
9780841231412
Peso dell'articolo
664 grammi
Dimensioni
15.88 x 2.54 x 23.5 cm

Rarewaves.com USA

London, London, Regno Unito

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Venditore AbeBooks dal 11 giugno 2025

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