Riassunto
Research on particulate delivery systems is an increasingly important discipline of the pharmaceutical sciences being performed in academic and industrial laboratories around the world. Particulate systems offer a great potential for the controlled delivery of drugs, diagnostic agents, antigens, and genetic material. This book presents trends and future strategies using:
liposomes
emulsions
polymeric nanoparticles
solid lipid nanoparticles
nanosuspensions of poorly soluble and bioavailable drugs
particulate diagnostics
Including contributions from leading European pharmaceutical research groups, the chapters cover pharmaceutical applications ranging from traditional formulations for drug targeting and delivery that increases therapeutic efficacy to cosmetic formulations. Future Strategies for Drug Delivery with Particulate Systems is an excellent resource for researchers and scientists interested in meeting the challenge of developing effective, low-cost systems for delivering the right drugs at the right rates and level of side effects.
Contenuti
Nanoparticles and Liposomes for Drug Targeting, E. Fattal, H. Alphandary, C. Weingarten, Ch. Vauthier, C. Dubernet, A. Andremont, and P. Couvreur
Design of a New Eye Delivery System for Oligonucleotide Based on a Liposomal Dispersion in a Gel, A. Bochot, E. Fattal, and P. Couvreur
Alginate Nanoparticles as a Noval Carrier for Antisense Oligonucleotides, I. Aynié, Ch. Vauthier, E. Fattal, M. Foulquier, and P. Couvreur
Splenic Trapping of Nanoparticles: Complementary Approaches for in situ Studies, M. Dimoy, S. Gibaud, J.P. Andreux, C. Weingarten, B. Gouritin, and P. Couvreur
Synthesis of a Noval Poly(MePEG-co-alkyl) Cyanoacrylate, Amphiphilic Copolymer for the Preparation of PEG-Coated Nanoparticles, M.T. Peracchia, D. Desmaéle, J. d'Angelo, and P. Couvreur
Lipid-Based Drug Delivery Systems for Peptide and Protein Drug Delivery, S. Frokjaer, K. Jørgensen, and Ch. Vermehren
Fat Emulsions Based on Structured Lipids as Delivery Systems for Intravenous Use, H. Hedeman, H Brøndsted, A. Müllertz, and S. Frokjaer
Relationship Between Lipid Bilayer Micro-Structure and Functional Properties of Liposomes, K. Jørgensen, M.C. Sabra, J. Risbo, and O.G. Mouritsen
Medium-Chain Lecithin in Nasal Drug Delivery Systems: Advantages and Drawbacks, Ch. Vermehren, H.S. Hansen, and M.K. Thomsen
Interaction of Plasma Proteins with Liposomes-Influence of Surface Properties on Adsorption Patterns and Protein Conformation, J.E. Diederichs
Iron Oxides as Contrast Agents in Magnetic Resonance Lymphography, M. Kresse
Solid Lipid Nanoparticles, Nanosuspensions and Liposomes for Pharmaceutical and Cosmetic Applications, R.H. Müller
Particulate Systems for the Controlled Delivery of Active Compounds in Pharmaceutics and Cosmetics, R.H. Müller
Solid Lipid Nanoparticles (SLN™) for Oral Administration-Drug Incorporation and Degradation, S.A. Runge and R.H. Müller
Nanosuspensions-A Noval Forumulation for Poorly Soluble Drugs, K. Peters and R.H. Müller
Two-Dimensional Electrophoresis (2-DE) for the Determination of Plasma Proteins Adsorbed on Model Drug Carriers, M. Lück, B.-P. Paulke, W. Schröder, and R.H. Muller
Development of a Liposomal Formulation for Hair Care Use, J. Herbort, J.E. Diederichs, and R.H. Müller
Liposomes as Drug Carrier for Diagnostics, Cytostatics and Genetic Material, R. Reszka
Preparation and Characterization of a New Generation of Cationic Liposomes for Gene Transfer, D. Groth, C. Lehman, O. Keil, M. Schneider, and R. Reszka
Characterization of Gene Transfer Vesicle by Electron Microscopy, C. Lehman, D. Groth, O. Keil, M. Schneider, M. Rudolph, and R. Reszka
Strategies for Site Specific, Time and Rate Controlled Delivery of Drugs, Genes and Antigenes, D.J.A. Crommelin, W.E. Hennink, and G. Storm
Development of an Optimized Immuno-Enzymosome Formulation for Application in Cancer Therapy, M.J. Fonseca, M.H. Vingerhoeds, H.J. Haisma, D.J.A. Crommelin, and G. Storm
Factors Influencing Lymphatic Disposition of Liposomes after Subcutaneous Administration, C. Oussoren and G. Storm
MHC II/Peptide Liposomes as Artificial Antigen Presenting Cells, A.J.M.L. van Rensen, L.S. Taams, M.CJ.T. Grosfeld-Stulemeyer, A. Besseling, W. van Eden, D.J.A. Crommelin, and M.H.M. Wauben
Targeting of Antibiotics to Bacterial Infections Using Long-Circulating Liposomes, R.M. Schiffelers, G. Storm, and I.A.J.M. Bakker-Woudenberg
Optimal Delivery of Desferrioxamine (DFO) in the Treatment of Murine Malaria, N.S. Postma, C.C. Hermsen, W.M.C. Eling, O. Boerman, and J. Zuidema
Poly ((2-dimethylamio) ethy methacrylate) Nanoparticles for Gene Transfection, H. Talsma, J.Y. Cherng, P.v.d. Wetering, D.J.A. Crommelin, and W.E. Hennink
Liposomal Delivery of Cytokines for Anticancer Vaccination, M.L. van Slooten, F.J. Koppenhagen, J.J. Bergers, R. Kircheis, D.J.A. Crommelin, E. Wagner, and G. Storm
Index
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