Gastrulation : Movements, Patterns and Molecules

Ray Keller

ISBN 10: 1468460293 / ISBN 13: 9781468460292

Editore: Springer US, 2013

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Druck auf Anfrage Neuware - Printed after ordering - Gastrulation is a fundamental process of early embryonic development. It involves virtually every aspect of cell and developmental biology and results in the formation of fundamental structural elements around which a developing animal's body plan is organized. As such it is not only an important process, but also one that is complicated and not easily dissected into its component parts. To understand the mechanisms of gastrulation one must acknowledge that gastrulation is fundamentally a biomechanical process (that is, a problem of cells generating forces in a three dimensional array, patterned in space and time such that appropriate tissue movements are executed). Three intertwined questions emerge: what cell activities generate forces, how are these cell activities patterned in space and time, and how are the resulting forces harnessed in three dimensional domains To address these issues it is important to define and characterize regional cell behaviors and to learn how they are patterned in the egg and/ or by subsequent cell and tissue interactions. At the biochemical level, what are the cellular and extracellular molecules that control cell behavior Finally, how are specific patterns of cellular activity integrated to produce tissue behavior The task of answering the above questions, an immense task in itself, is compounded by the fact that the morphogenetic movements of gastrulation and their underlying mechanisms vary between different organisms.

Codice articolo 9781468460292

Dati bibliografici

• Titolo: Gastrulation : Movements, Patterns and Molecules
• Editore: Springer US
• Data di pubblicazione: 2013
• Lingua: Inglese
• ISBN 10: 1468460293
• ISBN 13: 9781468460292
• Rilegatura: Taschenbuch
• Condizione: Neu
• Dimensioni: 235 L x 155 A x 19 P (millimetri) 235 millimetri di larghezza per 155 millimetri di altezza per 19 millimetri di profondità
• Peso: 528 grammi

Descrizione articolo

Riassunto

Gastrulation is a fundamental process of early embryonic development. It involves virtually every aspect of cell and developmental biology and results in the formation of fundamental structural elements around which a developing animal's body plan is organized. As such it is not only an important process, but also one that is complicated and not easily dissected into its component parts. To understand the mechanisms of gastrulation one must acknowledge that gastrulation is fundamentally a biomechanical process (that is, a problem of cells generating forces in a three dimensional array, patterned in space and time such that appropriate tissue movements are executed). Three intertwined questions emerge: what cell activities generate forces, how are these cell activities patterned in space and time, and how are the resulting forces harnessed in three dimensional domains? To address these issues it is important to define and characterize regional cell behaviors and to learn how they are patterned in the egg and/ or by subsequent cell and tissue interactions. At the biochemical level, what are the cellular and extracellular molecules that control cell behavior? Finally, how are specific patterns of cellular activity integrated to produce tissue behavior? The task of answering the above questions, an immense task in itself, is compounded by the fact that the morphogenetic movements of gastrulation and their underlying mechanisms vary between different organisms.

Contenuti

Cell Movements in the Epiblast During Gastrulation and Neurulation in Avian Embryos; G.C. Schoenwolf. Mesoderm Formation in the Chick Embryo, Revisited; C.D. Stern. Culture of Embryonic Cells for Analysis of Amphibian and Mammalian Early Embryogenesis; N. Nakatsuji, K. Hashimoto. Organizing the Xenopus Organizer; J. Gerhart, et al. The Arrangement of Early Inductive Signals in Relation to Gastrulation; J. Cooke. Cell Motility, Control and Function of Convergence and Extension During Gastrulation in Xenopus; R. Keller, et al. In Vivo Analysis of Convergent Cell Movements in the Germ Ring of Fundulus; J.P. Trinkaus, et al. Dynamical Models for Cell Rearrangement During Morphogenesis; M. Weliky, G. Oster. Mesoderm Cell Migration in the Xenopus Gastrula; R. Winklebauer, et al. Ten additional articles. Index.