Paperback. The discipline of statistical genetics is highly computational. Be it exact compu- tionalmethods,simulationbased,orahybridofthetwo,computationalpackagesare indispensable tools and constant companions of researchers in the ?eld. This ha- bookisintendedtoprovidehumangeneticistsandotherbiomedicalresearcherswith guidance on selections of appropriate computational methods and software pa- ages for their speci?c genetic problems. It may also be used by students and other learners as a reference in conjunction with a more theoretical and/or methodolo- cally oriented text book. This book tries to strike a balance between methodological expositions and practical guidelines for software selections. Wherever possible, comparisons among the competing methods and software are made to highlight the relativeadvantagesanddisadvantagesoftheapproaches,so thatthe readercanmake informed choices to best match their speci?c needs. Human genetics has been undergoing an evolution in the past several years as new knowledge and technologies are transforming the ?eld, leading to numerous new discoveriesof genes associated with complex traits such as cancer, obesity, and diabetes. Many recent genome-wide association studies employ the casecontrol design, where the study subjects consist of unrelated affected individuals and n- mal controls. For each individual, a large number of genetic markers are queried. Human genetics has been undergoing an evolution in the past several years as new knowledge and technologies are transforming the ?eld, leading to numerous new discoveriesof genes associated with complex traits such as cancer, obesity, and diabetes. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.

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Dati bibliografici

Titolo: Handbook on Analyzing Human Genetic Data (Paperback)
Editore: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, Berlin
Data di pubblicazione: 2014
Lingua: Inglese
ISBN 10: 3642424813
ISBN 13: 9783642424816
Rilegatura: Paperback
Condizione: new

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Riassunto

This handbook provides human geneticists and other biomedical researchers with guidance on selections of appropriate computational methods and software packages for their specific genetic problems. It may also be used by students and other learners as a reference in conjunction with a more theoretical and/or methodologically oriented text book. Coverage strikes a balance between methodological expositions and practical guidelines for software selections. Wherever possible, comparisons among competing methods and software are made to highlight the relative advantages and disadvantage of the approaches so that readers can make informed choices to best match their specific needs.

Dalla quarta di copertina

The discipline of statistical genetics is highly computational. Be it exact computational methods, simulation based, or a hybrid of the two, computational packages are indispensable tools and constant companions of researchers in the field. This handbook is intended to provide human geneticists and other biomedical researchers with guidance on selections of appropriate computational methods and software packages for their specific genetic problems. It may also be used by students and other learners as a reference in conjunction with a more theoretical and/or methodologically oriented text book. This book tries to strike a balance between methodological expositions and practical guidelines for software selections. Wherever possible, comparisons among competing methods and software are made to highlight the relative advantages and disadvantage of the approaches so that the readers can make informed choices to best match their specific needs.

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