Human Identification : The Use of DNA Markers

Weir, Bruce S. (EDT)

ISBN 10: 0792335201 ISBN 13: 9780792335207
Editore: Kluwer Academic Publishers, 1995
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The ongoing debate on the use of DNA profiles to identify perpetrators in criminal investigations or fathers in paternity disputes has too often been conducted with no regard to sound statistical, genetic or legal reasoning. The contributors to this text have considerable experience in forensic science, statistical genetics or jurimetrics, and many of them have had to explain the scientific issues involved in using DNA profiles to judges and juries. Although the authors hold differing views on some of the issues, they have all produced accounts which pay due attention to the issues of independence of components of the profiles and of population substructures.

Contenuti: 1. Introduction; B. S. Weir. 2. A Method for Characterizing Differentiation between Populations at Multi-Allelic Loci and Its Implications for Establishing Identity and Paternity; D. J. Balding, R. A. Nichols. 3. The Effect of Relatedness on Likelihood Ratios and the Use of Conservative Estimates; J. F. Y. Brookfield. 4. The Effects of Inbreeding on DNA Profile Frequency Estimates Using PCR-Based Loci; B. Budowle. 5. Correlation of DNA Fragment Sizes within Loci in the Presence of Non-Detectable Alleles; R. Chakraborty, Z. Li. 6. Inferences of Population Subdivision from the VNTR Distributions of New Zealanders; A. G. Clark, J.F. Hamilton, G.K. Chambers. 7. Conditioning on the Number of Bands in Interpreting Matches of Multilocus DNA Profiles; R. N. Curnow. 8. Match Probability Calculations for Multi-Locus DNA Profiles; P. Donnelly. 9. Population Genetics of STR Loci; I. Evett, P. Gill. 10. Assessing the Probability of Paternity and the Product Rule in DNA Systems; D. W. Gjertson, J. W. Morris. 11. The Forensic Debate on the NRC's DNA Report: Population Structure, Ceiling Frequencies and the Need for Numbers; D. H. Kaye. 12. Applications of the Dirichlet Distribution to Forensic Match Probabilities; K. Lange. 13. The Honest Scientist's Guide to DNA Evidence; R. Lempert. 14. Tests for Independence in the FBI Databases; P. J. Maiste, B. S. Weir. 15. Alternative Approaches to Population Structure; N. Morton. 16. DNA Evidence: Wrong Answers or Wrong Questions? B. Robertson, G. A. Vignaux. 17. SubjectiveInterpretation, Laboratory Error and the Value of Forensic Evidence: Three Case Studies; W. Thompson. 18. Exact Tests for Disequilibria with Arbitrary Numbers of Loci and Alleles; D. Zaykin, L.A. Zhivotovsky, B.S. Weir. 19. Bibliography for the Forensic Uses of DNA.

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Titolo: Human Identification : The Use of DNA Markers
Casa editrice: Kluwer Academic Publishers
Data di pubblicazione: 1995
Legatura: Rilegato
Condizione: New

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