Human Pluripotent Stem Cells: Engineering Tissue from Human Embryonic Stem Cells: Differentiation of Embryonic Stem Cells to Clinically Relevant Pop
Cebo, Daniel
ISBN 10: 1730769357 ISBN 13: 9781730769351
Editore: Independently published, 2018
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Codice articolo 34821774-n
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Recent advances in human embryonic stem cell (hESC) biology now offer an alternative cell source for tissue engineers, as these cells are capable of proliferating indefinitely and differentiating to many clinically relevant cell types. Novel culture methods capable of exerting spatial and temporal control over the stem cell microenvironment allow for more efficient expansion of hESCs, and significant advances have been made toward improving our understanding of the biophysical and biochemical cues that direct stem cell fate choices. Effective production of lineage specific progenitors or terminally differentiated cells enables researchers to incorporate hESC derivatives into engineered tissue constructs. Here, we describe current efforts using hESCs as a cell source for tissue engineering applications, highlighting potential advantages of hESCs over current practices as well as challenges which must be overcome
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Titolo: Human Pluripotent Stem Cells: Engineering ...
Casa editrice: Independently published
Data di pubblicazione: 2018
Legatura: Brossura
Condizione: New