Java for Bioinformatics and Biomedical Applications

Bal, Harshawardhan

ISBN 10: 0387372350 / ISBN 13: 9780387372358

Editore: Springer, 2006

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Most items will be dispatched the same or the next working day. A copy that has been read, but is in excellent condition. Pages are intact and not marred by notes or highlighting. The spine remains undamaged. Codice articolo wbs1760555044

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Titolo: Java for Bioinformatics and Biomedical ...

Casa editrice: Springer

Data di pubblicazione: 2006

Legatura: Rilegato

Condizione: Very Good

Descrizione articolo

Riassunto:

"The science and practice of medicine has undergone a fundamental change as a result of large-scale genome projects that led to the sequencing of a number of important microbial, plant and animal genomes in the last 5 years. This book aims to combine industry standard software engineering and design principles, genomics and bioinformatics and cancer research. It focuses on creating and integrating practical, useful tools for the scientific community in the context of real-life, real-value biomedical problems that researchers face on a routine basis, rather than being just a didactic exercise in learning a programming platform. The book leverages technologies for molecular biology, genomics and bioinformatics and cancer research developed by the NIH, NCI-Center for Bioinformatics (NCICB), the National Center for Biotechnology Information (NCBI, a division of the National Library of Medicine (NLM) at the NIH) and Stanford University."--Publisher.

Dalla quarta di copertina:

Java for Bioinformatics and Biomedical Applications describes the work of the U.S. National Cancer Institute (NCI, National Institutes of Health, U.S. Department of Health and Human Services) and a large number of cancer centers across the U.S. under the caBIG (cancer Biomedical Informatics Grid) program, as well as standard bioinformatics applications. The goal of NCI caBIG is to create a standards based, interoperable network of individuals, applications and data to enhance the pace of cancer research. CaBIG uses J2EE and open source standards for all software development work.  This book examines the tools and technologies being developed under caBIG to meet the goal of eliminating suffering and death from cancer by 2015 as formulated by the former NCI Director, Dr. Andrew von Eschenbach.In doing so, it provides a vignette into the efforts of thousands of people molecular biologists, medical practitioners, software developers, to name a few - across the country to bring the promise of translational research to individuals with cancer.

From a software perspective, a functional approach is used to teach the Java platform and its features for enterprise-level application development. Under this approach, the various syntactical and operative elements of the language and any software libraries that have been used (for example, BioJava, Apache, etc.) are taught not in isolation but in the context of discrete definable research problems that enable the user to relate how the different parts of the language fit together in the big picture. All examples are derived from practical problems faced in biomedical/clinical data retrieval and analysis during routine bioinformatics and cancer research. Further, the book illustrates how individual bioinformatics applications (such as BLAST and Genscan) can be stitched together into a pipeline so that users can direct the output of one tool (for example, gene predictions using Genscan) to perform further analysis (say, homology searching using BLAST).