Killer Cell Dynamics: Mathematical & Computational Approaches To Immunology

Wodarz D.

ISBN 10: 0387308938 ISBN 13: 9780387308937
Editore: Springer, 2006
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New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service. Codice articolo ABEOCT25-82161

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Riassunto:

Systems biology and computational biology have recently become prominent areas of research in the biomedical community, especially in the area of cell biology. Long before the popularity of systems biology in biomedicine, however, such approaches have been used successfully in a di?erent area of biology: population ecology.

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This book reviews how mathematics can be used in combination with biological data in order to improve understanding of how the immune system works. This is illustrated largely in the context of viral infections. Mathematical models allow scientists to capture complex biological interactions in a clear mathematical language and to follow them to their precise logical conclusions. This can give rise to counter-intuitive insights which would not be attained by experiments alone, and can be used for the design of further experiments in order to address the mathematical results.

This book provides both an introduction to the field of mathematical immunology, and an overview of many topics which are the subject of current research, covering a broad variety of immunological topics. It starts with basic principles of immunology and covers the dynamical interactions between the immune system and specific viral infections, including important human pathogens such as HIV. General biological and mathematical background material to both virus infection and immune system dynamics is provided, and each chapter begins with a simple introduction to the biological questions examined.

This book is intended for an interdisciplinary audience. It explains the concept of mathematical modeling in immunology and shows how modeling has been used to address specific questions. It is intended both for the mathematical biologists who are interested in immunology, and for the biological readership that is interested in the use of mathematical models in immunology. Dominik Wodarz is an Associate Professor at the Department of Ecology and Evolutionary Biology at the University of California, Irvine.

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Titolo: Killer Cell Dynamics: Mathematical & ...
Casa editrice: Springer
Data di pubblicazione: 2006
Legatura: Rilegato
Condizione: Brand New

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