Microarrays for an Integrative Genomics (Computational Molecular Biology)

Kohane, Isaac S., Butte, Atul J.

ISBN 10: 026211271X / ISBN 13: 9780262112710

Editore: Bradford Books, 2002

Riguardo questo articolo

Gut/Very good: Buch bzw. Schutzumschlag mit wenigen Gebrauchsspuren an Einband, Schutzumschlag oder Seiten. / Describes a book or dust jacket that does show some signs of wear on either the binding, dust jacket or pages. Codice articolo M0026211271X-V

Dati bibliografici

Titolo: Microarrays for an Integrative Genomics (...

Casa editrice: Bradford Books

Data di pubblicazione: 2002

Legatura: Rilegato

Condizione: very good

Descrizione articolo

Riassunto:

Functional genomics--the deconstruction of the genome to determine the biologicalfunction of genes and gene interactions--is one of the most fruitful new areas of biology. Thegrowing use of DNA microarrays allows researchers to assess the expression of tens of thousands ofgenes at a time. This quantitative change has led to qualitative progress in our ability tounderstand regulatory processes at the cellular level.This book provides a systematic introductionto the use of DNA microarrays as an investigative tool for functional genomics. The presentation isappropriate for readers from biology or bioinformatics. After presenting a framework for the designof microarray-driven functional genomics experiments, the book discusses the foundations foranalyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature anddata models, clinical applications of functional genomics research, and the future of functionalgenomics.

L'autore:

Isaac S. Kohane is Director of the Children's Hospital Informatics Program, Associate Professor of Pediatrics at Harvard Medical School, and an Attending Physician in Endocrinology at Children's Hospital, Boston.