Microbial Biotransformation: L-DOPA Production | Using a novel fungus Penicillium jensenii

Devipriya Majumder (u. a.)

ISBN 10: 3659148180 / ISBN 13: 9783659148187

Editore: LAP Lambert Academic Publishing, 2012

Microbial Biotransformation: L-DOPA Production | Using a novel fungus Penicillium jensenii | Devipriya Majumder (u. a.) | Taschenbuch | Englisch | LAP Lambert Academic Publishing | EAN 9783659148187 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Codice articolo 106423237

Riassunto:

Biotransformation is the chemical modification(or alteration) of chemical compounds like amino acids, toxins, xenobiotics and drugs, brought about by an organism to produce bioactive molecules. Penicillium jensenii isolated from soil (rhizosphere zone) was found to be a potent tyrosinase producer. Tyrosinase is capable of bringing about biotransformation of a single amino acid tyrosine to L-DOPA (3, 4- dihydroxyphenylalanine) and alpha methyl DOPA. L-DOPA is converted into dopamine in the brain and body by the enzyme L-aromatic amino acid decarboxylase which is further responsible for all kinds of the voluntary movements of the body. The by-product Alpha methyl DOPA is equally commercially viable as an important anti hypertensive and psychoactive drug. Since L-DOPA remains the gold standard for the treatment of Parkinson's disease, its production using microorganisms can hold a promising future for the small molecule pharmaceutical industry.

Informazioni sull?autore: Dr. (Mrs.) Devipriya Rabin Majumder (PhD Microbiology): HOD Microbiology, Abeda Inamdar Senior College, Pune.Ms. Komal Mukeshkumar Raval (M.Sc Microbiology): Research Assistant, Abeda Inamdar Senior College, Pune.Ms. Pooja Suresh Vaswani (M.Sc Microbiology): Research Assistant, Abeda Inamdar Senior College, Pune.

Dati bibliografici

Titolo: Microbial Biotransformation: L-DOPA ...
Casa editrice: LAP Lambert Academic Publishing
Data di pubblicazione: 2012
Legatura: Taschenbuch
Condizione: Neu