Model Systems in Biology : History, Philosophy, and Practical Concerns

Georg Striedter

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Lingua: inglese

Editore: MIT Press Ltd Aug 2022, 2022

0262046946 / 9780262046947

Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH

Venditore con 5 stelle

Venditore AbeBooks dal 14 agosto 2006

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Descrizione dell’articolo da parte del venditore

Neuware - How biomedical research using various animal species and in vitro cellular systems has resulted in both major successes and translational failure.In Model Systems in Biology, comparative neurobiologist Georg Striedter examines how biomedical researchers have used animal species and in vitro cellular systems to understand and develop treatments for human diseases ranging from cancer and polio to Alzheimer's disease and schizophrenia. Although there have been some major successes, much of this 'translational' research on model systems has failed to generalize to humans. Striedter explores the history of such research, focusing on the models used and considering the question of model selection from a variety of perspectives-the philosophical, the historical, and that of practicing biologists. Striedter reviews some philosophical concepts and ethical issues, including concerns over animal suffering and the compromises that result. He traces the history of the most widely used animal and in vitro models, describing how they compete with one another in a changing ecosystem of models. He examines how therapies for bacterial and viral infections, cancer, cardiovascular diseases, and neurological disorders have been developed using animal and cell culture models-and how research into these diseases has both taken advantage of and been hindered by model system differences. Finally, Striedter argues for a 'big tent' biology, in which a diverse set of models and research strategies can coexist productively.…

Codice articolo 9780262046947

Titolo
Model Systems in Biology : History, Philosophy, and Practical Concerns
Autore
Georg Striedter
Editore
MIT Press Ltd Aug 2022
Anno di pubblicazione
2022
Condizione
Neu
Rilegatura
Buch
Lingua
inglese
ISBN 10
0262046946
ISBN 13
9780262046947
Peso dell'articolo
700 grammi
Dimensioni
261x185x25 mm

AHA-BUCH GmbH

Einbeck, Germania

Venditore con 5 stelle

Venditore AbeBooks dal 14 agosto 2006

Tariffe di spedizione da Germania a U.S.A.

ArticoloDa 7 a 10 giorni lavorativiDa 5 a 7 giorni lavorativi
Primo articoloEUR 35,00EUR 45,00
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