Neurogenic Inflammation in Health and Disease

ISBN 10: 0444532293 / ISBN 13: 9780444532299

Editore: Elsevier Science Dez 2008, 2008

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This item is printed on demand - it takes 3-4 days longer - Neuware -Morphological and functional studies revealed a complex system of primary sensory neurons that parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel that transmits pain. 368 pp. Englisch.

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Dati bibliografici

• Titolo: Neurogenic Inflammation in Health and Disease
• Editore: Elsevier Science Dez 2008
• Data di pubblicazione: 2008
• Lingua: Inglese
• ISBN 10: 0444532293
• ISBN 13: 9780444532299
• Rilegatura: Buch
• Condizione: Neu
• Dimensioni: 241 L x 165 A x 23 P (millimetri) 241 millimetri di larghezza per 165 millimetri di altezza per 23 millimetri di profondità
• Peso: 816 grammi

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Riassunto

Morphological and functional studies revealed a complex system of primary sensory neurons which parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel which transmits pain.

* Neurogenic inflammation in historical perspective
* Cardiac protection by nociceptive afferents
* Molecular mechanisms of nociception
* Sensory mechanisms in migraine pathophysiology
* Vagal signalling of visceral inflammation
* Neurogenic mechanisms in arthritis
* Therapeutic implications of vanilloid-type compounds