Neurological Therapeutics: Principles and Practice, 2 Volume Set (Addendum included)

A comprehensive and authoritative textbook, Neurological Therapeutics: Principles and Practice provides a reference that is both authoritative and accessible for daily use. The textbook explores the issues underlying treatment decisions not only for the most readily treated disorders but also for those conditions with few existing, definitive therapeutic options. With 600 figures, 37 in full color, tables, and a companion volume that is portable and easy-to-use, the final product is an important reference.

PRINCIPLES OF THERAPEUTICS
Section Editor: John H. Noseworthy
Basic Pharmaceutical Principles and the Blood Brain-Barrier
Molecular Therapies for the Nervous System and Muscle
Clinical Trial Methodology, FDA Terminology and Procedures
Placebos
Evidence-Based Medicine
Ethical Issues in Neurological Treatment and Clinical Trials
Domestic Violence in Neurological Practice

PAIN: HEADACHE, SPINE AND LIMB PAIN
Section Editor: John G. Emeads
Principles of Pain Management
Migraine
Cluster Headache
Tension-Type Headache
Chronic Daily Headache
Post-Traumatic Headaches
Indomethacin-Responsive Headache Syndromes
Giant Cell Arteritis
Headache "Syndromes" in Children and Adolescents
Diagnosis and Treatment of Common Orofacial Pain Conditions
Radicular Limb Pain
Back Pain
Complex Regional Pain Syndrome (Reflex Sympathetic Dystrophy, Causalgia, Shoulder-Hand Syndrome)
The Treatment of Central Pain
Peripheral (Neuropathic) Pain Disorders
Cancer Pain
Fibromyalgia and Myofascial Pain Syndrome
Pain Disorders

SEIZURE DISORDERS
Section Editor: Martha J. Morrell
Classification and Epidemiology of Seizure Disorders: Therapeutic Implications and Importance
The Pathophysiology of the Epilepsies
Principles in Epilepsy: Diagnosis and Pharmacotherapy
Antiseizure Drugs
Surgery and Nonpharmacologic Therapies for Epilepsy
Status Epilepticus
The Treatment of Epilepsy in Children and Infants
Seizures and Epilepsy in Women
Epilepsy in the Elderly
Imitators of Epilepsy
Legal and Regulatory Issues for People With Epilepsy

CEREBROVASCULAR DISEASE
Section Editor: Jose Biller
Principles of Atherosclerosis and Atherogenesis
Stroke Prevention
Anticoagulant Therapy and Antiplatelet Drugs
Thrombolytic Therapy for Stroke
Asymptomatic Carotid Artery Stenosis
Transient Ischemic Attacks
Management of Patients With Acute Ischemic Stroke
Cardioembolic Stroke
Cerebral Complications After Cardiac Surgery and Cardiac Arrest
Hypoxic-Ischemic Encephalopathy
Treatment of Intracerebral Hemorrhage
Subarachnoid Hemorrhage Due to Cerebral Aneurysms
Cerebral Aneurysms and Vascular Malformations
Unruptured Intracranial Aneurysms
Cervicocephalic Arterial Dissections
Fibromuscular Dysplasia
Venous Disorders
Spinal Cord Vascular Syndromes
Disorders of Coagulation
Antiphospholipid Antibodies and Variants
Systemic and Central Nervous System Vasculitides
Hypertensive Encephalopathy
Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
Moyamoya Disease
Stroke in Children
Stroke in Pregnancy

NEURO-ONCOLOGY
Section Editor: J. Gregory Cairncross
A Perspective on Neuro-Oncology
Chemotherapy and Antineoplastic Agents
Radiotherapy for CNS Neoplasms: Principles, Technologies and Indications
Surgically Curable Brain Tumors of Adults
Diagnosis and Treatment of Pituitary Tumors
Diffuse Cerebral Gliomas in Adults
Malignant Brain Tumors of Childhood
Germ Cell Tumors and Primary Central Nervous System Lymphoma
Brain Metastases
Primary Tumors of the Spinal Cord, Root, Plexus, and Nerve Sheath
Metastases to the Spine Meninges and Plexus
Treatment of Paraneoplastic Neurological Syndromes
Metabolic and Nutritional Complications
Neurological Complications of Antineoplastic Treatment

INFLAMMATORY AND INFECTIVE DISEASES
Section Editors: Karen L. Roos and Hans-Peter Hartung
Bacterial Meningitis
Infectious Intracranial Mass Lesions
Viral Meningitis and Encephalitis
Tuberculosis and Other Mycobacterial Infections
Neurosyphilis
Lyme Disease
Tetanus
Rickettsial Infections
Neurological Complications of HIV Infection
Neurological Complications of HTLV-1 Infection
Rabies
Fungal Infections
Protozoal Infections
Helminthic Infections of the Central Nervous System
Neurology of Arachnida (Spiders, Ticks, Scorpions) and Hymenoptera (Ants, Bees, Wasps) Envenomations
Prion Diseases: Transmissible Spongiform Encephalopathies
Perinatal Infections
Infection in Solid Organ and Bone Marrow Transplant Recipients
Behçet Disease: Diagnosis and Management
Autoimmunity in the Nervous System
Multiple Sclerosis and Related Conditions

ICU NEUROLOGY
Section Editor: Elco F.M. Wijdicks
Therapy for Critically Ill Neurological Patients
Airway Management and Mechanical Ventilation
Management of Blood Pressure in Acute Neurological Illnesses
Management of Increased Intracranial Pressure. Management of Sedation and Pain in the Intensive Care Unit
Disturbances of Fluid and Electrolytes in Critically Ill Neurological Patients
Anticoagulation and Thrombolysis in the Intensive Care Unit
Management of Generalized Weakness in Medical and Surgical Intensive Care Units
Organ Transplant Complications in the Intensive Care Unit
Aspects of Metabolic Coma in the Intensive Care Unit
Management of Head Trauma and Spinal Cord Injury in Adults
Management of Nutrition

NEUROLOGIC COMPLICATIONS OF SYSTEMIC ILLNESS (INCLUDING SLEEP DISORDERS, TOXIC, METABOLIC, NUTRITIONAL AND ENVIRONMENTAL DISORDERS)
Section Editor: Martin A. Samuels
Neurological Complications of Cardiac Procedures: Catheterization, Interventional Procedures and Surgery
Cardiac Arrhythmias and Sudden Death
Endocarditis (Infective and Non-Infective)
Syncope
Cardiomyopathy
Cardiac Tumors
Arterial Hypertension and Hypertensive Encephalopathy
Hepatic Encephalopathy-Diagnosis and Management
Acute Respiratory Failure in Neurological Disease
Disorders of Excessive Sleepiness
Parasomnias
Disorders of Water and Sodium Balance
Acid-Base Disturbances and the Central Nervous System
Use of Therapeutic Plasma Exchange and Intravenous Immunoglobulin for the Treatment of Neurological Disease
Megaloblastic Anemias-Vitamin B12, Folate
Hemoglobinopathies and Thalassemias: Treatment of Stroke and Other Neurological Complications
Therapy of the Neurological Complications of Lymphoma and Leukemia
Neurological Disorders in Benign and Malignant Plasma Cell Dyscrasias
Neurological Manifestations of Systemic Disease: Cryoglobulinemia
Neurological Aspects of Transplantation
Immunodeficiency Diseases
Vasculitis Involving the Nervous System
Neurological Manifestations of Rheumatoid Arthritis
Cervical Spondylosis, Ankylosing Spondylitis, and Lumbar Disc Disease
Neurological Complications of Progressive Systemic Sclerosis
Treatment of Neurosarcoidosis
Hypothalamus, Anterior and Posterior Pituitary and Adrenal (Including Disorders of Temperature Regulation)
The Neurological Manifestations of Thyroid Disease
Reproductive Endocrinology and Gender-Specific Issues in Neurology
Disorders of Bone and Mineral Metabolism
Lysosomal Storage Diseases
Whipple Disease of the Nervous System
Alcohol
Stimulants, Sedatives, and Opiates
Treatment of the Neurotoxic Effects of Organic Solvents
Treatment of the Neurotoxic Effects of Gases: Carbon Monoxide, Hydrogen Sulfide, and the Nitrogen Oxides
Pesticides
Toxemia of Pregnancy
Neuropathies and Neuromuscular Junction Disorders of Pregnancy
Pregnancy and Multiple Sclerosis: Therapeutic Aspects
Movement Disorders During Pregnancy
Mitochondrial Disease

PEDIATRIC AND ADOLESCENT NEUROLOGY
Section Editor: Russell D. Snyder
The Neurological Examination of the Infant and Child
Perinatal Neurology
Developmental Problems of the Brain, Skull and Spine
Mental Retardation and Cerebral Palsy
Disorders of Learning and Behavior in Children
Chromosomal Disorders, Inborn Errors of Metabolism and Degenerative Diseases
Neurocutaneous Disorders
Pediatric Brain and Spinal Cord Injury

CRANIAL NERVE DISORDERS (INCLUDING NEURO-OTOLOGY AND NEURO-OPHTHALMOLOGY)
Section Editor: James A. Sharpe
Disturbances of Smell and Taste
Optic Neuropathies
Papilledema and Idiopathic Intracranial Hypertension (Pseudotumor Cerebri)
Chiasm and Retrochiasmal Disorders
Disturbances of the Pupil
Ocular Motor Nerve Palsies
Nystagmus and Saccadic Oscillations
Gaze Disorders
Ocular Myasthenia Gravis
Cavernous Sinus Disorders
Trigeminal Neuropathy and Neuralgia. Disorders of the Facial Nerve
Vertigo, Vestibular Nerve, and Central Vestibular Disorders
Disorders of the Inner Ear
Tinnitus and Deafness
Disorders of the Glossopharyngeal, Vagus, Accessory, and Hypoglossal Nerves. Multiple Cranial Nerve Palsies
Functional Diseases Affecting the Cranial Nerves

PERIPHERAL NERVE DISORDERS (INCLUDING ANTERIOR HORN CELL, AND AUTONOMIC NERVOUS SYSTEM)
Section Editor: Peter J. Dyck
Mechanical Nerve Injuries
Varicella Zoster Virus, Herpes Simplex Virus, Bell's Palsy
Peripheral Nervous System Lyme Disease
Diphtheritic Neuropathy
Peripheral Neuropathy and HIV
The Neuropathies of Leprosy
Peripheral Neuropathies in Chagas Disease
Late Effects of Polio
Diabetic Polyneuropathy
Diabetic Radiculoplexus Neuropathies
Peripheral Neuropathy Associated With Hypothyroidism and Acromegaly
Multiple Endocrine Neoplasia, Type 2B
Neuropathies in Liver Disease and Chronic Renal Failure
Peripheral Neuropathy Associated with Alcoholism, Malnutrition, and Vitamin Deficiencies
Acute Inflammatory Demyelinating Polyradiculoneuropathy, Acute Motor Axonal Neuropathy and Acute Motor and Sensory Axonal Neuropathy
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Miller Fisher Syndrome
Brachial Plexus Neuropathy
Nondiabetic Lumbosacral Radiculoplexus Neuropathy
Treatment of Non-malignant Sensory Ganglionopathies
Vasculitis of the Peripheral Nervous System
The Treatment of Multi-focal Motor Neuropathy With Conduction Block (MMN-CB)
Sarcoidosis and Peripheral Neuropathy
Neuropathy Associated With the Monoclonal Gamopathies. Amyloidosis
Peripheral Neuropathy in the Lymphomas and Leukemias
Paraneoplastic Neuropathy Syndromes: Principles and Treatment
Inherited Neuropathies With Known Metabolic Derangement
Porphyria. Hereditary Sensory and Autonomic Neuropathies
Hereditary Motor Neuropathies
Hereditary Neuropathy With Liability to Pressure Palsy
Hereditary Spinocerebellar Degeneration
Motor Neuron Diseases. Neurotoxic Metals
Critical Illness Polyneuropathy
Paresthesias and Pain
Treatment of Sexual Dysfunction and Cystopathy in Peripheral Nerve Disorders
Gastrointestinal Dysmotility and Sphincter Dysfunction
Neurogenic Orthostatic Hypotension
Orthostatic Intolerance
Treatment of Central Autonomic Disorders

MUSCLE DISEASES
Section Editor: Andrew E. Engel
Principles of Muscle Disorders
Congenital Myopathies
Muscular Dystrophies
Inflammatory Myopathies
Metabolic Myopathies
Disorders of Voltage-Gated Ion Channels
Myasthenia Gravis and Myasthenic Syndromes
Malignant Hyperthermia
Stiff-Man Syndrome
Cramps and Myalgias

DEGENERATIVE DISEASES (MOVEMENT DISORDERS)
Section Editors: Stanley Fahn and Blair Ford
Principles of Movement Disorders
Medical Treatment of Parkinson's Disease and Its Complications
Parkinsonism Plus Disorders
Surgical Treatment of Parkinson's Disease
The Diagnosis and Treatment of Normal Pressure Hydrocephalus
Syringomyelia. Focal Dystonias: Blepharospasm, Cervical Dystonia, Spasmodic Dysphonia, Writer's Cramp
Generalized Torsion Dystonia. Dopa-Responsive Dystonia (DRD)
Huntington Disease
Neuroacanthocytosis
Sydenham Chorea
Ballism and Chorea
Essential Tremor
Treatment of Orthostatic Tremor
Myoclonus
Dentatorubral-pallidoluysian Atrophy (DRPLA)
Tardive Dyskinesia and Related Syndromes
Tourette Syndrome and Tic Disorders
Paroxysmal Dyskinesias
Painful Legs and Moving Toes
The Restless Legs Syndrome and Periodic Movements of Sleep
Treatment of Hemifacial Spasm
Wilson's Disease
Psychogenic Movement Disorders
Hereditary Ataxias and Other Cerebellar Degenerations
Therapy of Human Prion Diseases
Hereditary Spastic Paraplegia

NEUROBEHAVIOR AND NEUROPSYCHIATRY
Section Editor: Kenneth M. Hellman
Treatment of Disorders of Cognition: An Introduction
Aphasia
Treatment of Alexia and Agraphia
Treatment of Developmental Language Disorders
Treatment of Neglect
Management of Attention-Deficit/Hyperactivity Disorder and Dyslexia (Specific Reading Disability)
Limb Apraxia
Intentional Disorders
Evaluation and Management of Amnesic Disorders
Executive Disorders
Alzheimer Disease and Mild Cognitive Impairment
Diagnosis and Management of the Non-Alzheimer Dementias
Behavioral and Emotional Complications of Neurological Disorders
Treatment of Emotional Communication Disorders