New Approaches of Protein Function Prediction from Protein Interaction Networks

Jingyu Hou

ISBN 10: 0128098147 / ISBN 13: 9780128098141

Editore: Academic Press 2017-01-11, 2017

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Dati bibliografici

• Titolo: New Approaches of Protein Function Prediction from Protein Interaction Networks
• Editore: Academic Press 2017-01-11
• Data di pubblicazione: 2017
• Lingua: Inglese
• ISBN 10: 0128098147
• ISBN 13: 9780128098141
• Rilegatura: Paperback
• Condizione: New

Descrizione articolo

Riassunto

New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks. Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated via biological experiments, there are still many proteins whose functions are yet to be annotated due to the limitations of existing methods and the high cost of experiments. To overcome experimental limitations, this book helps users understand the computational approaches that have been rapidly developed for protein function prediction.

Informazioni sull?autore

Dr. Jingyu Hou has been undertaking research in bioinformatics, especially in protein function prediction from protein-protein interaction (PPI) networks for many years. Dr Hou is part of a strong bioinformatics research team from Deakin University in Australia and has published many high quality journal and international conference papers. Particularly for protein function prediction, Jingyu’s research team has proposed and published various innovative algorithms to dynamically predict protein functions from PPI networks. These algorithms refer to many critical aspects of protein function prediction, including semantic similarities of proteins, dynamic selection of prediction domains, iterative function predictions and so on which are advanced and interesting in this area.