Nuclear Receptors : The Art and Science of Modulator Design and Discovery

Lingua: inglese

Editore: Springer, 2021

3030783146 / 9783030783143

Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH

Venditore con 5 stelle

Venditore AbeBooks dal 14 agosto 2006

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Condizione: Nuovo

EUR 300,36

EUR 43,34 spedizione 
Spedito da Germania a U.S.A.

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Descrizione dell’articolo da parte del venditore

Druck auf Anfrage Neuware - Printed after ordering - Nuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is proposed, and indeed documented, to affect many physiological and pathological conditions in experimental animals and humans. Thus, nuclear receptors have become a major target in the effort to treat numerous diseases.This book will shed light on and emphasize intricate processes involved in designing as well as discovering physiological and pharmacological modulators of these important proteins.World-renowned scientists will share with the reader their professional expertise and extensive experience acquired through decades working with nuclear receptors. Chapters addressthe various means and consequences of modulating nuclear receptor activity will be presented and discussed.These modulators cover a wide span of moieties ranging from synthetic chemicals to natural products. In addition, the classification of these chemicals ranges from pan agonists to selective agonists and inverse agonists to antagonists. They also include proteolytic means to obliterate the receptor in the event that modulating its activity through canonical pharmacological agents becomes less effective and/or less desirable due to anticipated or experienced toxicities. Modulation of receptor activity may also take place in the absence of a ligand or through manipulating the structure of the receptor itself by controlling posttranslational events. …

Codice articolo 9783030783143

Titolo
Nuclear Receptors : The Art and Science of Modulator Design and Discovery
Autore
Mostafa Z. Badr
Editore
Springer
Anno di pubblicazione
2021
Condizione
Neu
Rilegatura
Buch
Lingua
inglese
ISBN 10
3030783146
ISBN 13
9783030783143
Peso dell'articolo
1191 grammi
Dimensioni
241x160x43 mm

AHA-BUCH GmbH

Einbeck, Germania

Venditore con 5 stelle

Venditore AbeBooks dal 14 agosto 2006

Tariffe di spedizione da Germania a U.S.A.

ArticoloDa 7 a 10 giorni lavorativiDa 5 a 7 giorni lavorativi
Primo articoloEUR 43,34EUR 59,29
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