Pathophysiology : Clinical Concepts of Disease Processes

The new edition of this well-respected text uses a body system approach to studying diseases. This comprehensive textbook, with its traditional presentation of content, integrates basic science with clinical practice and focuses on the alterations in biologic processes that affect the body's equilibrium. Highly readable, it includes shorter, more focused chapters, and end-of-chapter study questions.

• A body systems approach presents the material in a logical order.
• Introductory chapters are included on concepts that affect all body systems to provide a foundation for understanding disease processes.
• Anatomy and physiology are reviewed for each body system to provide a basis for understanding the alterations in function affecting that system.
• Eighty-two short chapters break content into more manageable sections and make a difficult subject easier to teach and learn.
• Outlines with page numbers at the beginning of each chapter help students focus on the most important concepts and provide easy access to chapter content.
• Study questions are provided for every chapter to help students review material and assess their knowledge and understanding. Answers are included for immediate feedback.
• About 725 illustrations clarify difficult concepts and demonstrate normal and disease processes.
• 70 full-color plates depict disease manifestations and enhance the text descriptions of these conditions.

Color Plates
PART ONE: INTRODUCTION TO GENERAL PATHOLOGY: MECHANISMS OF DISEASE
1. General Concepts of Disease: Health Versus Disease
2. Heredity, Environment, and Disease: Interaction of Heredity and Environment
3. Cellular Injury and Death
4. Response of the Body to Injury: Inflammation and Repair
5. Response of the Body to Immunologic Challenge
6. Response of the Body to Infectious Agents
7. Disturbances in Circulation
8. Disturbances in Growth, Cellular Proliferation, and Differentiation
PART TWO: IMMUNE SYSTEM DISORDERS
9. Familiar (IgE-Mediated) Allergic Disorders: Anaphylaxis and the Atopic Diseases
10. Bronchial Asthma: Allergic and Otherwise
11. Atopic Dermatitis and Urticaria
12. Autoimmune and Immune Complex-Induced Diseases
13. Adverse Reactions to Drugs and Related Substances
14. Approaches to Immune Deficiency States
15. Human Immunodeficiency Virus (HIV) and Immunodeficiency Syndrome (AIDS)
PART THREE: HEMATOLOGIC SYSTEM DISORDERS
16. The Composition of Blood and the Monocyte-Macrophage System
17. Red Blood Cell Disorders
18. White Blood Cell and Plasma Cell Disorders
19. Coagulation Disorders
PART FOUR: FLUID AND ELECTROLYTE DISORDERS
20. Fluid and Electrolyte Balance and Assessment
21. Disorders of Fluid Volume, Osmolality, and Electrolytes
22. Acid-Base Disorders
PART FIVE: GASTROINTESTINAL SYSTEM DISORDERS
23. Disorders of the Esophagus
24. Disorders of the Stomach and Duodenum
25. Disorders of the Small Intestine
26. Disorders of the Large Intestine
27. Disorders of the Liver, Gallbladder, and Pancreas
PART SIX: CARDIOVASCULAR SYSTEM DISORDERS
28. Anatomy of the Cardiovascular System
29. Physiology of the Cardiovascular System
30. Diagnostic Procedures in Cardiovascular Disease
31. Coronary Atherosclerotic Disease
32. Valvular Heart Disease
33. Cardiac Mechanical Dysfunction and Circulatory Support
34. Vascular Disease
PART SEVEN: RESPIRATORY SYSTEM DISORDERS
35. Anatomy and Physiology of the Respiratory System
36. Diagnostic Procedures in Respiratory Disease
37. Cardinal Signs and Symptoms of Respiratory Disease
38. Obstructive Patterns of Respiratory Disease
39. Restrictive Patterns of Respiratory Disease
40. Cardiovascular Disease and the Lung
41. Respiratory Failure
42. Pulmonary Malignant Neoplasms
43. Pulmonary Tuberculosis
PART EIGHT: RENAL SYSTEM DISORDERS
44. Anatomy and Physiology of the Kidneys and Urinary Tract
45. Diagnostic Procedures in Renal Disease
46. Chronic Renal Failure
47. End-Stage Renal Disease: Uremic Syndrome
48. Treatment of Chronic Renal Failure
49. Acute Renal Failure
PART NINE: NEUROLOGIC SYSTEM DISORDERS
50. Anatomy and Physiology of the Nervous System
51. Evaluation of the Neurologic Patient
52. Pain
53. Cerebrovascular Disease
54. Neurologic Disorders with Generalized Symptomatology
55. Seizure Disorders
56. Central Nervous System Injury
57. Central Nervous System Tumors
PART TEN: ENDOCRINE SYSTEM AND METABOLIC DISORDERS
58. Principles of Endocrine and Metabolic Control Mechanisms
59. Disorders of the Pituitary Gland
60. Thyroid Gland Disorders
61. Adrenal Hypersecretion Disorders
62. Adrenal Insufficiency
63. Pancreas: Glucose Metabolism and Diabetes Mellitus
PART ELEVEN: REPRODUCTIVE SYSTEM DISORDERS
64. Female Reproductive System Disorders
65. Male Reproductive System Disorders
66. Infections of the Genital Tract
PART TWELVE: MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DISORDERS
67. Anatomy and Physiology of Bones and Joints
68. Fractures and Dislocations
69. Tumors of the Musculoskeletal System
70. Osteoarthritis
71. Rheumatoid Arthritis
72. Systemic Lupus Erythematosus
73. Scleroderma
74. Gout
75. Seronegative Spondyloarthropathies
PART THIRTEEN: DERMATOLOGIC SYSTEM DISORDERS
76. Anatomy and Physiology of the Skin
77. Acne and Related Conditions
78. Eczema and Vascular Disorders
79. Psoriasis and Pityriasis Rosea
80. Cutaneous Infections
81. Tumors of the Skin
82. Lyme Disease and Infections
Answers to Study Questions
Index