This book contains a broad survey on the peroxiredoxins. It involves almost all groups that contributed significant insights into the emerging field. Coverage discusses the diverse biological roles of the new protein family in the context of other antioxidant systems like those based on heme or selenium catalysis. In addition, the book highlights related future perspectives.
Contributing Authors Preface Chapter 1. Introduction: History of the Peroxiredoxins and Topical Perspectives Leopold Flohé and J. Robin Harris Chapter 2. Evolution of the Peroxiredoxins (Taxonomy/Homology/Characterization) Bernard Knoops, Eléonore Loumaye and Valérie Van der Eecken Chapter 3. Structural Survey of the Peroxiredoxins P. Andrew Karplus and Andrea Hall Chapter 4. The Catalytic Mechanism of Peroxiredoxins Leslie B. Poole Chapter 5. Kinetics of Peroxiredoxins and their Role in the Decomposition of Peroxynitrite Madia Trujillo, Gerardo Ferrer-Sueta, Leonor Thomson, Leopold Flohé and Rafael Radi Chapter 6. The Peroxiredoxin Repair Proteins Thomas J. Jönsson and W. Todd Lowther Chapter 7. Peroxiredoxins in Bacterial Antioxidant Defense James M. Dubbs and Skorn Mongkolsuk Chapter 8. The NADH oxidase-Prx system in Amphibacillus xylanus Youichi Niimura Chapter 9. Peroxiredoxin Systems in Mycobacteria Timo Jaeger Chapter 10. Peroxiredoxin systems of protozoal parasites Marcel Deponte, Stefan Rahlfs and Katja Becker Chapter 11. The Trypanaothione System Luise R. Krauth-Siegel, Marcelo A. Comini and Tanja Schlecker Chapter 12. Functions of Typical 2-Cys Peroxiredoxins in Yeast Brian A. Morgan and Elizabeth A. Veal Chapter 13. The Dual Function of Plant Peroxiredoxins in Antioxidant Defence and Redox Signaling Karl-Josef Dietz Chapter 14. Mitochondrial Peroxiredoxins: Structure and Function Zhenbo Cao, J. Gordon Lindsay and Neil W. Isaacs Chapter 15. Peroxiredoxins in the Lung with Emphasis on Peroxiredoxin VI Bruno Schremmer, Yefim Manevich, Sheldon I. Feinstein, and Aron B. Fisher. Chapter 16. Peroxiredoxins in Gametogenesis andEmbryo Development Isabelle Donnay and Bernard Knoops Chapter 17. Peroxiredoxins in the Central Nervous System Fumiyuki Hattori and Shinzo Oikawa Chapter 18. Stress-induced Peroxiredoxins Tetsuro Ishii and Toru Yanagawa Index