Petsko, G: Protein Structure and Function

Petsko, Gregory A. (Director of the Rosentiel Center, Brandeis University)|Ringe, Dagmar (Professor of Biochemistry and Chemistry, Brandeis University)

ISBN 10: 0199556849 / ISBN 13: 9780199556847

Editore: Oxford University Press, 2008

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Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Protein Structure and Function provides a critical survey of our current understanding protein structure and function in the age of genomics. Moving from sequence to structure, and structure to function, the book also explores the link between sequence and .

Codice articolo 594427191

Dati bibliografici

• Titolo: Petsko, G: Protein Structure and Function
• Editore: Oxford University Press
• Data di pubblicazione: 2008
• Lingua: Inglese
• ISBN 10: 0199556849
• ISBN 13: 9780199556847
• Rilegatura: Kartoniert / Broschiert
• Condizione: New

Descrizione articolo

Riassunto

How does the chemical description of a protein relate to its three-dimensional structure? How does the three-dimensional structure relate to the machinery that brings about a chemical reaction? How does the sequence of a gene encode not only the sequence of a protein but, more importantly, the architecture and function of that protein?

Protein Structure and Function provides a clear and critical survey of our current understanding of the structure and function of proteins to answer questions such as these. Opening with a consideration of the link between protein sequence and structure, it goes on to explore the structural basis of protein function and how this function is controlled. Finally, it examines a range of case studies that illuminate the range of roles performed by proteins, and the diverse structures these proteins exhibit.

Protein Structure and Function combines articulate prose with striking full colour illustrations, while the unique Primers in Biology modular structure integrates text, illustrations, definitions, and literature references for each topic into one double-page spread, bringing to the student's fingertips all the tools that they need to master that topic.

Online Resource Centre
The Online Resource Centre features figures from the book available to download, for registered adopters of the book.

Informazioni sull?autore

Gregory A Petsko studied chemistry and classics as an undergraduate at Princeton University before going to Oxford as a Rhodes scholar to work for his PhD with David Phillips. He then pursued his interest in the mechanism of enzyme catalysis at the Massachusetts Institute of Technology where he taught courses in chemistry and detective fiction, before moving to Brandeis where he is currently Director of the Rosenstiel Center and has extended his research interests to include the use of yeast genetics to study the unfolded protein response pathway, and the mechanism of action of the ABC transporter proteins.


Dagmar Ringe graduated in chemistry from Barnard College, Columbia, and took her PhD in bioorganic chemistry from Boston University. She then pursued her research interest in the study of enzyme catalysis by X-ray crystallography at the Massachusetts Institute of Technology before moving to Brandeis where she is Professor of Biochemistry and Chemistry and where the principal focus of her research is on structure-function relationships in enzymes of particular industrial and pharmaceutical importance.