Pharmacological Preconditioning with Opioids for Myocardial Protection | Role of Delta-Opioid Receptor Agonists

Daniel Sigg

ISBN 10: 383835379X / ISBN 13: 9783838353791

Editore: LAP LAMBERT Academic Publishing, 2010

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Pharmacological Preconditioning with Opioids for Myocardial Protection | Role of Delta-Opioid Receptor Agonists | Daniel Sigg | Taschenbuch | 208 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838353791 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.

Codice articolo 101216148

Dati bibliografici

• Titolo: Pharmacological Preconditioning with Opioids for Myocardial Protection | Role of Delta-Opioid Receptor Agonists
• Editore: LAP LAMBERT Academic Publishing
• Data di pubblicazione: 2010
• Lingua: Inglese
• ISBN 10: 383835379X
• ISBN 13: 9783838353791
• Rilegatura: Taschenbuch
• Condizione: Neu
• Dimensioni: 220 L x 150 A x 13 P (millimetri) 220 millimetri di larghezza per 150 millimetri di altezza per 13 millimetri di profondità
• Peso: 328 grammi
• Cataloghi dei venditori:
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Descrizione articolo

Riassunto

The objective of this research was to investigate the role of opioids in myocardial protection of the large mammalian heart. A porcine isolated working heart model of swine was carefully characterized and various opioid agonists were administered prior to inducing global ischemia. An acute coronary occlusion model was developed to investigate the effects of opioid preconditioning on regional ischemia, in particular infarct size, myocardial function, and arrhythmias. The results of these studies suggest a specific role of δ-receptor agonists in myocardial protection in large mammalian hearts.

L'autore

Daniel obtained his M.D. degree from the University of Basel,Switzerland. After getting board-certified in Anesthesia, hecompleted graduate studies in Physiology with a Ph.D. at theUniversity of Minnesota. He lives in Saint Paul, MN, with hisfamily, and currently works in medical research and consulting.