Riassunto:
Aging is an inevitable aspect of living. This book covers the aging process from a physiological viewpoint, examining all systems of the body and describing changes that occur with normal aging and in disease. Its primary focus is on humans, but some animal and in vitro research is included to explain mechanisms and theories of aging. Integrated aspects of aging (e.g., demography of aging) are considered, and preventive and interventive measures (pharmacology, diet, exercise) for ensuring healthful aging are discussed. The Second Edition of Physiological Basis of Aging and Geriatrics considers many new approaches and methods for studying the aging process. New and updated information on molecular and cellular mechanisms, pathology, and aging-related diseases is provided to promote a better understanding of basic biological mechanisms. Theories, epidemiology, demographics, and comparative and differential aging are also presented.
Contenuti:
General Perspectives: Introduction: Aging as a Stage in the Life Cycle (P.S. Timiras). Definitions: Demographic, Comparative, and Differential Aging (P.S. Timiras). Aging and Disease (P.S. Timiras). Theories of Aging (R. Sharma). Molecular and Cellular Aging: Degenerative Changes in Cells and Cell Death (P.S. Timiras). Oxidants and Antioxidants in Aging (R.J. Melhorn). Aging of the Immune System (H. Sternberg). Systemic and Organismic Aging: Aging of the Nervous System: Structural and Biochemical Changes (P.S. Timiras). Aging of the Nervous System: Functional Changes (P.S. Timiras). Aging of the Sensory Systems (E. Meisami). Aging of the Adrenals and Pituitary (P.S. Timiras). Aging of the Female Reproductive System (B.J. Merry and H. Holehan). Aging of the Male Reproductive System (B.J. Merry and H. Holehan). Aging of the Thyroid Gland and Basal Metabolism (P.S. Timiras). The Endocrine, Pancreas, and Carbohydrate Metabolism (P.S. Timiras). Cardiovascular Alterations with Age: Atherosclerosis, Coronary Heart Disease, Hypertension ((P.S. Timiras). Plasma Lipoproteins: Their Metabolism and Role in Atherosclerosis (T.M. Forte). Aging of Respiration (P.S. Timiras). Erythrocytes and the Hematopoietic System (R.W. Atherton). The Kidney, the Lower Urinary Tract, the Prostate, and Body Fluids (M.L. Timiras). Aging of the Gastrointestinal Tract and Liver (P.S. Timiras). Aging of the Skeleton, Joints, and Muscles (P.S. Timiras). Aging of the Skin and Connective Tissue (M.L. Timiras). Prevention and Rehabilitation: Pharmacology and Drug Management in the Elderly (J.L. Beizer and M.L. Timiras). Effects of Diet on Aging (B.J. Merry and H. Holehan). An Agenda for Healthful Aging (P.S. Timiras and P.E. Segall).
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