Editor(s): Menon, K. M. J.; Goldstrohm, Aaron C. Num Pages: 355 pages, 44 black & white illustrations, 7 colour illustrations, 5 black & white tables, 43 colour. BIC Classification: MFG; MFN; MJG. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 21. Weight in Grams: 695. . 2015. Hardback. . . . . Books ship from the US and Ireland.

Codice articolo V9783319251226

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Titolo: Post-Transcriptional Mechanisms in Endocrine Regulation
Editore: Springer International Publishing AG
Data di pubblicazione: 2016
Lingua: Inglese
ISBN 10: 3319251228
ISBN 13: 9783319251226
Rilegatura: Rilegato
Condizione: New

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Riassunto

This book examines how post-transcriptional mechanisms control endocrine function. This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones. The impacts of these mechanisms on disease and health are covered, providing a novel update to the scientific literature.

Post-transcriptional regulatory mechanisms play an essential role in controlling dynamic gene expression. The outcome of this regulation includes control of the amount, timing, and location of protein expression. Regulation is mediated by cis-acting RNA sequences and structures and transacting RNA binding proteins and non-coding RNAs, including microRNAs. Recent advances in characterization of these regulatory factors have revealed enormous regulatory potential.

Informazioni sull?autore

K.M.J. Menon, PhD, is Professor in the Departments of Biological Chemistry & Obstetrics and Gynecology at the University of Michigan Medical School.

Aaron C. Goldstrohm, PhD, is Associate Professor in the Department of Biological Chemistry at the University of Michigan Medical School.

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