A Practical Guide to Designing Phase II Trials in Oncology

Sarah R Brown

ISBN 10: 1118570901 / ISBN 13: 9781118570906

Editore: Wiley Mai 2014, 2014

Riguardo questo articolo

Neuware - 'Choosing Your Phase II Trial Design provides an overview to clinical trial researchers of the steps involved in designing a phase II trial and provides a way to identify a range of optimal designs. Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, it sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomisation. A detailed library of trial designs is featured along with examples and case studies accompanied by illustrations using a flow diagram, highlighting the choices made for each key point throughout the process. For those new to trial design, the book provides an introduction to the concepts behind informed decision making in phase II trials, offering a unique and practical learning tool. For those familiar with phase II trial design, the reader will benefit from exposure to new, less familiar trial designs, providing alternative options to those which the reader may not have previously used'--Provided by publisher.

Codice articolo 9781118570906

Dati bibliografici

• Titolo: A Practical Guide to Designing Phase II Trials in Oncology
• Editore: Wiley Mai 2014
• Data di pubblicazione: 2014
• Lingua: Inglese
• ISBN 10: 1118570901
• ISBN 13: 9781118570906
• Rilegatura: Buch
• Condizione: Neu
• Dimensioni: 231 L x 155 A x 18 P (millimetri) 231 millimetri di larghezza per 155 millimetri di altezza per 18 millimetri di profondità
• Peso: 454 grammi

Descrizione articolo

Riassunto

How to identify optimal phase II trial designs

Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, A Practical Guide to Designing Phase II Trials in Oncology sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomization, and considering both academic and industry perspectives. A comprehensive and systematic library of available phase II trial designs is included, saving time otherwise spent considering multiple manuscripts, and real-life practical examples of using this approach to design phase II trials in cancer are given.

A Practical Guide to Designing Phase II Trials in Oncology:

• Offers a structured and practical approach to phase II trial design
• Considers trial design from both an academic and industry perspective
• Includes a structured library of available phase II trial designs
• Is relevant to both clinical and statistical researchers at all levels
• Includes real life examples of applying this approach

For those new to trial design, A Practical Guide to Designing Phase II Trials in Oncology will be a unique and practical learning tool, providing an introduction to the concepts behind informed decision making in phase II trials. For more experienced practitioners, the book will offer an overview of new, less familiar approaches to phase II trial design, providing alternative options to those which they may have previously used.

Informazioni sull?autore

Sarah Rose Brown, Walter M. Gregory, Christopher J. Twelves, and Julia M. Brown, Clinical Trials Research Unit, University of Leeds, UK