Principles of Molecular Recognition

A. D. Buckingham

ISBN 10: 0751401250 / ISBN 13: 9780751401257

Editore: Springer Netherlands, Springer Netherlands, 1993

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Druck auf Anfrage Neuware - Printed after ordering - The importance of molecular recognition in chemistry and biology is reflected in a recent upsurge in relevant research, promoted in particular by high-profile initiatives in this area in Europe, the USA and Japan. Although molecular recognition is necessarily microscopic in origin, its consequences are de facto macroscopic. Accordingly, a text that starts with intermolecular interactions between simple molecules and builds to a discussion of molecular recognition involving larger scale systems is timely. This book was planned with such a development in mind. The book begins with an elementary but rigorous account of the various types of forces between molecules. Chapter 2 is concerned with the hydrogen bond between pairs of simple molecules in the gas phase, with particular reference to the preferred relative orientation of the pair and the ease with which this can be distorted. This microscopic view continues in chapter 3 wherein the nature of interactions between solute molecules and solvents or between two or more solutes is examined from the experimental standpoint, with various types of spectroscopy providing the probe of the nature of the interactions. Molecular recognition is central to the catalysis of chemical reactions, especially when bonds are to be broken and formed under the severe con straint that a specific configuration is to result, as in the production of enan tiotopically pure compounds. This important topic is considered in chapter 4.

Codice articolo 9780751401257

Dati bibliografici

• Titolo: Principles of Molecular Recognition
• Editore: Springer Netherlands, Springer Netherlands
• Data di pubblicazione: 1993
• Lingua: Inglese
• ISBN 10: 0751401250
• ISBN 13: 9780751401257
• Rilegatura: Buch
• Condizione: Neu
• Dimensioni: 241 L x 160 A x 19 P (millimetri) 241 millimetri di larghezza per 160 millimetri di altezza per 19 millimetri di profondità
• Peso: 541 grammi

Descrizione articolo

Riassunto

Molecular recognition is a rapidly expanding subject of critical importance to all disciplines concerned with the way molecules of all sizes interact. This book provides a grounding to the topic for those engaged, or about to be engaged, in these activities. Intermolecular forces, fundamental factors affecting molecular recognition, are discussed first and a chapter on small molecules highlights the information which can be applied more generally to larger systems. Later chapters deal with the core topics of molecules in solvents, asymmetric synthesis by catalysis, and the catalytic action of metalloenzymes. The book is completed with coverage of drug discovery and protein dynamics - areas central to the worldwide interest in this field.

Recensione

This text provides excellent background reading for chemists who have an interest in molecular recognition...it is interesting to read and includes over 350 up-to-date references - Chemistry in Britain; ...excellent background reading for chemists who have a interest in molecular recognition, or for those who are keen to move into one of these areas. - Chemistry in Britain.