Principles and Practice of Infectious Diseases: 2-Volume Set

Widely acknowledged as the definitive reference source of its kind, Principles and Practice of Infectious Diseases is back-in a new 6th Edition! Authored by a "who's who" of experts from around the world, this 2-volume set encompasses all that is currently known about the epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents. Completely revised and updated-and with a bold, new 4-color format-it is a complete, essential compendium of knowledge on this vast and complex subject.

Now includes a bound-in CD-ROM containing all of the images from the book available for PowerPoint download.

• Offers state-of-the-art guidelines for disease control and treatment
• Covers disease by microbe and by clinical syndrome, making it easy to find any subject of interest.
• Features complete coverage of all aspects of HIV and AIDS

• Features a new, extensive section on biodefense, with discussions of major pathogens
• Includes new chapters on hospital preparedness for infections such as SARS, infections in elderly patients, infections in returning travellers, nutrition and infection, alternative therapies for infection, the design and evaluation of clinical trials, and more!
• Discusses new antibiotics, including Daptomycin, telithromycin, gemifloxacin, as well as new antifungal and antiviral agents
• Presents fresh perspectives from a wealth of new contributors

VOLUME 1

Part I. Basic Principles in the Diagnosis and Management of Infectious Diseases
SECTION A. MICROBIAL VIRULENCE FACTORS
1. A Molecular Perspective of Microbial Pathogenicity
2. Microbial Adherence
3. Toxins
SECTION B. HOST DEFENSE MECHANISMS
4. Innate (General or Nonspecific) Host Defense Mechanisms
5. Human Genetics and Infection
6. Antibodies
7. Complement
8. Granulocytic Phagocytes
9. Cell-Mediated Defense against Infection
10. Nutrition, Immunity, and Infection
11. Evaluation of the Patient with Suspected Immunodeficiency
SECTION C. EPIDEMIOLOGY OF INFECTIOUS DISEASES
12. Epidemiologic Principles
13. Emerging and Re-emerging Infectious Disease Threats
14. Hospital Preparedness for Emerging and Highly Contagious Infections Diseases: Getting Ready for SARS or Whatever Comes Next
SECTION D.
15. The Clinician and the Microbiology Laboratory
SECTION E. ANTI-INFECTIVE THERAPY
16. Principles of Anti-infective Therapy
17. Molecular Mechanisms of Antibiotic Resistance in Bacteria
18. Pharmacokinetics and Pharmacodynamics of Anti-infective Agents
19. Penicillins
20. Cephalosporins
21. Other b-Lactam Antibiotics
22. b-Lactam Allergy
23. Fusidic Acid
24. Aminoglycosides
25. Tetracyclines and Chloramphenicol
26. Rifamycins
27. Metronidazole
28. Macrolides, Clindamycin, and Ketolides
29. Glycopeptides (Vancomycin and Teicoplanin), Streptogramins (Quinupristin-Dalfopristin), and Lipopeptides (Daptomycin)
30. Polymyxins (Polymixin B and Colistin)
31. Oxazolidinones
32. Sulfonamides and Trimethoprim
33. Quinolones
34. Urinary Tract Agents: Nitrofurantoin and Methenamine
35. Topical Antibacterials
36. Antimycobacterial Agents
37. Systemic Antifungal Agents
38. Antiviral Drugs (Other Than Antiretrovirals)
39. Immunomodulators
40. Hyperbaric Oxygen
41. Agents Active against Parasites and Pneumocystis
42. Complementary and Alternative Medicines for Infectious Diseases
43. Antimicrobial Management and Cost Containment
44. Interpretating the Results of Clinical Trials on Antimicrobial Agents
45. Outpatient Intravenous Antibiotic Therapy
46. Tables of Antimicrobial Agent Pharmacology

PART II. Major Clinical Syndromes
SECTION A. FEVER
47. Temperature Regulation and the Pathogenesis of Fever
48. Fever of Unknown Origin
49. The Acutely Ill Patient with Fever and Rash
SECTION B. UPPER RESPIRATORY TRACT INFECTIONS
50. The Common Cold
51. Pharyngitis
52. Acute Laryngitis
53. Acute Laryngotracheobronchitis (Croup)
54. Otitis Externa, Otitis Media, and Mastoiditis
55. Sinusitis
56. Epiglottitis
57. Infections of the Oral Cavity, Neck, and Head
SECTION C. PLEUROPULMONARY AND BRONCHIAL INFECTIONS
58. Acute Bronchitis
59. Chronic Obstructive Pulmonary Disease, Chronic Bronchitis, and Acute Exacerbations
60. Bronchiolitis
61. Acute Pneumonia
62. Pleural Effusion and Empyema
63. Lung Abscess
64. Chronic Pneumonia
65. Cystic Fibrosis
SECTION D. URINARY TRACT INFECTION
66. Urinary Tract Infections
SECTION E. SEPSIS
67. Sepsis, Severe Sepsis, and Septic Shock
SECTION F. INTERABDOMINAL INFECTION
68. Peritonitis and Intraperitoneal Abscesses
69. Infections of the Liver and Biliary System
70. Pancreatic Infections
71. Splenic Abscess
72. Appendicitis
73. Diverticulitis and Typhlitis
SECTION G. CARDIOVASCULAR INFECTIONS
74. Endocarditis and Intravascular Infections
75. Infections of Prosthetic Valves and Other Cardiovascular Devices
76. Prophylaxis of Infective Endocarditis
77. Myocarditis and Pericarditis
78. Mediastinitis
SECTION H. CENTRAL NERVOUS SYSTEM INFECTIONS
79. Approach to the Patient with Central Nervous System Infection
80. Acute Meningitis
81. Cerebrospinal Fluid Shunt Infections
82. Chronic Meningitis
83. Encephalitis, Myelitis, and Neuritis
84. Brain Abscess
85. Subdural Empyema, Epidural Abscess, and Suppurative Intracranial Thrombophlebitis
SECTION I. SKIN AND SOFT TISSUE INFECTIONS
86. Cellulitis and Subcutaneous Tissue Infections
87. Myositis
88. Lymphadenitis and Lymphangitis
SECTION J. GASTROINTESTINAL INFECTIONS AND FOOD POISONING
89. Principles and Syndromes of Enteric Infection
90. Esophagitis
91. Nausea, Vomiting, and Noninflammatory Diarrhea
92. Antibiotic-Associated Colitis
93. Inflammatory Enteritides
94. Enteric Fever and Other Causes of Abdominal Symptoms with Fever
95. Foodborne Disease
96. Tropical Sprue/Enteropathy
97. Whipple's Disease
SECTION K. BONE AND JOINT INFECTIONS
98. Infectious Arthritis of Native Joints
99. Osteomyelitis
100. Infections with Prostheses in Bones and Joints
SECTION L. DISEASES OF THE REPRODUCTIVE ORGANS AND SEXUALLY TRANSMITTED DISEASES
101. Genital Skin and Mucous Membrane Lesions
102. Urethritis
103. Vulvovaginitis and Cervicitis
104. Infections of the Female Pelvis
105. Prostatitis, Epididymitis, and Orchitis
SECTION M. EYE INFECTIONS
105. Microbial Conjunctivitis
107. Microbial Keratitis
108. Endophthalmitis
109. Infectious Causes of Uveitis
110. Periocular Infections
SECTION N. HEPATITIS
111. Acute Viral Hepatitis
112. Chronic Viral Hepatitis
SECTION O. ACQUIRED IMMUNODEFICIENCY SYNDROME
113. Global Perspectives on Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome
114. Epidemiology and Prevention of Acquired Immunodeficiency Syndrome and Human Immunodeficiency Virus Infection
115. Diagnosis of Human Immunodeficiency Virus Infection
116. The Immunology of Human Immunodeficiency Virus Infection
117. General Clinical Manifestations of Human Immunodeficiency Virus Infection (Including the Acute Retroviral Syndrome and Oral, Cutaneous, Renal, Ocular, and Cardiac Diseases)
118. Pulmonary Manifestations of Human Immunodeficiency Virus Infection
119. Gastrointestinal and Hepatobiliary Manifestations of Human Immunodeficiency Virus Infection
120. Neurologic Diseases Caused by Human Immunodeficiency Virus-1 and Opportunistic Infections
121. Malignancies in Human Immunodeficiency Virus Infection
122. Human Immunodeficiency Virus Infection in Women
123. Pediatric Human Immunodeficiency Virus Infection
124. Antiretroviral Therapy for Human Immunodeficiency Virus Infection
125. Management of Opportunistic Infections Associated with Human Immunodeficiency Virus Infection
126. Vaccines for Human Immunodeficiency Virus-1 Infection
SECTION P. MISCELLANEOUS SYNDROMES
127. Chronic Fatigue Syndrome
Index, i

VOLUME 2

PART III. Infectious Diseases and Their Etiologic Agents
SECTION A. VIRAL DISEASES
128. Introduction to Viruses and Viral Diseases
129. Orthopoxviruses: Vaccinia (Smallpox Vaccine), Variola (Smallpox), Monkeypox, and Cowpox
130. Other Poxviruses That Infect Humans: Parapoxviruses, Molluscum Contagiosum, and Yatapox
131. Introduction to Herpesviridae
132. Herpes Simplex Virus
133. Varicella-Zoster Virus
134. Cytomegalovirus
135. Epstein-Barr Virus (Infectious Mononucleosis)
136. Human Herpesvirus Types 6 and 7
137. Kaposi's Sarcoma−Associated Herpesvirus (Human Herpesvirus Type 8)
138. Herpes B Virus
139. Adenovirus
140. Papillomaviruses
141. JC, BK, and Other Polyomaviruses; Progressive Multifocal Leukoencephalopathy
142. Hepatitis B Virus and Hepatitis Delta Virus
143. Parvovirus B19
144. Orthoreoviruses and Orbiviruses
145. Coltiviruses and Seadornaviruses (Colorado Tick Fever)
146. Rotaviruses
147. Alphaviruses
148. Rubella Virus (German Measles)
149. Flaviviruses (Yellow Fever, Dengue, Dengue Hemorrhagic Fever, Japanese Encephalitis, West Nile Encephalitis, St. Louis Encephalitis, Tick-Borne Encephalitis)
150. Hepatitis C
151. Hepatitis G Virus and TT Virus
152. Coronaviruses, Including Severe Acute Respiratory Syndrome (SARS)-Associated Coronavirus
153. Parainfluenza Viruses
154. Mumps Virus
155. Respiratory Syncytial Virus
156. Human Metapneumovirus
157. Measles Virus (Rubeola)
158. Zoonotic Paramyxoviruses: Hendra, Nipah, and Menangle Viruses
159. Vesicular Stomatitis and Related Viruses
160. Rabdoviruses
161. Marburg and Ebola Virus Hemorrhagic Fevers
162. Influenza Virus
163. California Encephalitis, Hantavirus Pulmonary Syndrome, and Bunyavirid Hemorrhagic Fevers
164. Lymphocytic Choriomeningitis Virus, Lassa Virus, and the South American Hemorrhagic Fevers
165. Human T-Cell Lymphotropic Virus Types I and II
166. Human Immunodeficiency Viruses
167. Introduction to the Enteroviruses
168. Poliovirus
169. Coxsackieviruses, Echoviruses, and Newer Enteroviruses
170. Hepatitis A Virus
171. Rhinovirus
172. Noroviruses and Other Caliciviruses
173. Astroviruses and Picobirnaviruses
174. Hepatitis E Virus
SECTION B. PRION DISEASES
175. Prions and Prion Diseases of the Central Nervous System (Transmissible Neurodegenerative Diseases)
SECTION C. CHLAMYDIAL DISEASES
176. Introduction to Chlamydial Diseases
177. Chlamydia trachomatis (Trachoma, Perinatal Infections, Lymphogranuloma Venereum, and Other Genital Infections)
178. Chlamydophila (Chlamydia) psittaci (Psittacosis)
179. Chlamydophila (Chlamydia) pneumoniae
SECTION D. MYCOPLASMA DISEASES
180. Introduction to Mycoplasma Diseases
181. Mycoplasma pneumoniae and Atypical Pneumonia
182. Genital Mycoplasmas: Mycoplasma genitalium, Mycoplasma hominis, and Ureaplasma urealyticum
SECTION E. RICKETTSIOSES AND EHRLICHIOSES
183. Introduction to Rickettsioses and Ehrlichioses
184. Rickettsia rickettsii and Other Spotted Fever Group Rickettsiae (Rocky Mountain Spotted Fever and Other Spotted Fevers)
185. Ricketts...