Principles and Practice of Sleep Medicine, 3rd ed.

This book has been thoroughly revised with 45 new chapters on the knowledge base of sleep medicine. The first half of the book reviews the basic sciences related to sleep. The remainder of the book is followed by a review of sleep pathology in adults. This book covers the major topics of sleep apnea: narcolepsy, movement disorders, psychiatric disorders and insomnia. The methodology used in the sleep laboratory is also reviewed. New nomenclature has been used throughout.

1. Normal Sleep and Its Variations
History Of Sleep Physiology And Medicine
Normal Human Sleep: An Overview
Normal Ageing
Daytime Sleepiness And Alertness
Sleep Deprivation
Phylogeny Of Sleep Regulation
Mammalian Sleep

2. Sleep Mechanisms
Brain Electrical Activity And Sensory Processing During Waking And Sleep States
Brainstem Mechanisms Generating REM Sleep
Basic Mechanisms Of Sleep-Wake States
Control Of Motoneurons During Sleep

3. Physiology in Sleep
Physiological Regulation in Sleep
Cardiovascular Physiology: Central and Autonomic Regulation
Cardiovascular Physiology: The Peripheral Circulation
Respiratory Physiology: Central Neural Control
Respiratory Physiology: Control of Ventilation
Respiratory Physiology: Breathing in Normal Subjects
Respiratory Physiology: Sleep at High Altitudes
Host Defense
Endocrine Physiology
Gastrointestinal Physiology
Temperature Regulation
**Sleep-related Penile Erections

4. Chronobiology
Introduction: Chronobiology
Circadian Rhythms in Mammals: Formal Properties and Environmental Influences
Anatomy and Physiology of the Mammalian Circadian System
Molecular Genetic Basis for Mammalian Circadian System
The Human Circadian Timing System and Sleep-Wake Regulation
**Sleep Homeostasis and Models of Sleep Regulation
Circadian Rhythms in Fatigue, Alertness and Performance
Melatonin in the Regulations of Sleep & Circadian Rhythms

5. Pharmacology
Hypnotics: Basic Mechanisms and Pharmacology
Hypnotics: Efficacy and Adverse Effects
Stimulants: Basic Mechanisms and Pharmacology
Stimulants: Efficacy and Adverse Effects
Drugs Which Disturb Sleep and Wakefulness

6. Psychobiology and Dreaming
Approaches to the Study of Dream Content: Methods Measures
Theories of Dreaming
Dreaming, Imagery and Perception
Psychophysiology of Dreams
Waking Experiences & Dreaming
Dreams and Psychopathology

II Abnormal Sleep
7. Impact, Presentation, Diagnosis
Approach to the Patient with Disordered Sleep
Cardinal Manifestations of Sleep Disorders
Use of Clinical Tools and Tests in Sleep Medicine
Classification of Sleep Disorders
Epidemiology of Sleep Disorders
Sleep Medicine, Public Policy, and Public Health

8. Disorders of Chronobiology
Introduction: Disorders of Chronobiology
Jet Lag and Sleep Disruption
Shift Work
Circadian Disorders of Sleep-Wake Cycle

9. Insomnia
Evaluation and Management of Insomnia: An Overview
Transient and short-term insomnia
Primary Insomnia
Psychiatric Disorders & Insomnia
**Behavioral Therapy for Insomnia
Sleep Hygiene

10. Primary Disorders of Daytime Sleepiness
Pathophysiology of Narcolepsy
Narcolepsy
Idiopathic Central Nervous System Hypersomnia

11. Parasomnias
**NREM Arousal Parasomnias: Confusional arousals, sleep terrors and sleepwalking
**Epilepsy and Sleep Disorders
REM Sleep Parasomnias
**Restless Legs Syndrome and Periodic Limb Movement Disorder
Dreaming Disorders
Bruxism
Violent Parasomnias: Forensic Medicine Issuess

12. Sleep Breathing Disorders
**Medications, Sleep and Breathing
Snoring
Central Sleep Apnea
Anatomy and Physiology of Upper Airway Obstruction
Cardiorespiratory Changes in Sleep Disorders
Breathing
Clinical Features and Evaluation of Obstructive Sleep Apnea-Hypopnea Syndrome
Medical Therapy for Obstructive Sleep Apnea-Hypopnea Syndrome
Continuous Positive Airway Pressure for Sleep Breathing Disorders
Surgical Therapy for Obstructive Sleep Apnea-Hypopnea Syndrome
Oral Appliances for Sleep Breathing Disorders
Management of Obstructive Sleep Apnea-Hypopnea Syndrome: Overview
Asthma
Chronic Obstructive Pulmonary Disease
Restrictive Lung Disorders
Non-Invasive Ventilation for Sleep Breathing Disorders

13. Medical and Neurological Disorders
Sleep Related Cardiac Risk
Cardiac Arrhthmias
Cardiovascular Disease during Sleep
Chronic Fatigue Syndrome and Fibromyalgia
Parkinsonism
Dementia
Cerebrovascular Disease
Neuromuscular Disorders
Sleep and Infectious Disease
Endocrine Disorders
Gastrointestinal Disorders

14. Psychiatric Disorders
Anxiety Disorders
Mood Disorders
Schizophrenia
Eating Disorders
**Medication and Substance Abuse

15. Methodology
Monitoring and Staging Human Sleep
Monitoring Respiratory and Cardiac Function
Assessment of Sleep-related Erections
Assessment Techniques for Insomnia
Evaluating Sleepiness
Light Therapy
Neurological Monitoring Techniques
Gastrointestinal Monitoring Techniques
Psychometric & Psychiatric Evaluation
Actigraphy
**Computers in Sleep Medicine