Rethinking Cancer: A New Paradigm for the Postgenomics Era (Vienna Series in Theoretical Biology)

Lingua: inglese

Editore: MIT Press Ltd, 2021

0262045214 / 9780262045216

Serie: Libro 11 di 17 - Vienna Series in Theoretical Biology

Da: World of Books (was SecondSale), Montgomery, IL, U.S.A.World of Books (was SecondSale)

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Descrizione dell’articolo da parte del venditore

Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence. Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. After dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet never before has it been so unclear what to do with this knowledge. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical evidence. The contributors first discuss the new research framework in terms of theoretical foundations and then take up the relevance of a systems approach, reviewing such topics as nonlinearity, recurrence after treatment, the cellular attractor concept, network theory, and non-coding DNA--the dark matter of our genome. They address the temporality of cancer progression, drawing on evolutionary theory and clinical experience. Finally, they cover the dominant role of the tissue microenvironment in cancer, analyzing topics including altered metabolic pathways, the disease-defining influence on metastasis, and the interconnectedness of different environmental niches across levels of organization.…

Codice articolo 00110090977

Titolo
Rethinking Cancer: A New Paradigm for the Postgenomics Era (Vienna Series in Theoretical Biology)
Autore
Bernhard Strauss
Editore
MIT Press Ltd
Anno di pubblicazione
2021
Condizione
Very Good
Rilegatura
Hardback
Lingua
inglese
ISBN 10
0262045214
ISBN 13
9780262045216
Serie
Libro 11 di 17: Vienna Series in Theoretical Biology

World of Books (was SecondSale)

Montgomery, IL, U.S.A.

Venditore con 5 stelle

Venditore AbeBooks dal 20 dicembre 2007

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ArticoloDa 4 a 12 giorni lavorativiDa 3 a 6 giorni lavorativi
Primo articoloEUR 0,00EUR 9,62
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