Sensory Nerves

Lingua: inglese

Editore: Springer, 2009

3540790896 / 9783540790891

Serie: Libro 21 di 124 - Handbook of Experimental Pharmacology

Da: Myboeken BV, Duiven, Paesi BassiMyboeken BV

Venditore con 5 stelle

Venditore AbeBooks dal 14 aprile 2023

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Condizione: Nuovo

EUR 258,00

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Spedito da Paesi Bassi a U.S.A.

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Descrizione dell’articolo da parte del venditore

Theintentionofthisbookistoprovideacomprehensiveandcontemporaryreview ofthebiologyofsensorynerves. InkeepingwiththethemeoftheHandbookof Experimental Pharmacology series, emphasis will be placed on the actions of drugs,transmittersandautacoidsthatinitiateorinhibitsensorynerveactivation (through actionsonionchannelsandreceptorsattheirperipheralterminals)or modulate the release or actions of the transmitters released from the central terminalsofsensorynerves. Onthebasisofextensivesupportiveevidenceinthe literature, it is our view that many diseases are characterized by alterations in sensorynervefunction(e. g. pain,cardiovasculardiseaseandmigraine). Itisour beliefthatthisbookwillbeunique,asitwillcomprehensivelycovertheroleof sensory nerves across many therapeutic areas. To address directly one of the editorialboardqueries,thisisnotintendedtobeabookaboutthepharmacology ofpain. Thatsaid,tomostpharmacologists,painisthemostobviousindicationfor aroleorsensorynervesindisease. Webelievethatthelessonslearntfromthestudy ofneuropathicpainwillbeinvaluableforresearchersintheothertherapeuticareas covered inthisvolume. Sincemostinterest hasfocusedontheroleofsensory nervesinneuropathicpain,wehaveaddedanumberofchaptersdevotedtothis subject. Thebookisorganizedinthreeparts,coveringthetypesandrolesofsensory nervesinsomaticandvisceraldisorders(PartI),speci?ctargetsonsensorynerves relevanttopainandvisceraldisorders(PartII)andadescriptionofcurrentand futuretherapeuticstrategiesfortargetingsensorynerves(PartIII). The?rsttwochaptersinPartIaredevotedtodescribingtheclinicalfeaturesof neuropathicpainandvisceralpain. Ourintentionisfortheauthorstoprovidea clinicalviewpointonthefeaturesoftheseconditionsandtheadvantages/disadv- tagesofcurrenttreatmentmodalities. Thenext?vechaptersinPartIfocusonthe roleofsensorynervesinotherpathologicalconditions. Severalcommonthemes willemergeinthispart,includingthemodeofsensorynerveactivationinvarious tissues and organs, the alterations in sensory nerve excitability associated with disease,andtheimportanceofin?ammationandin?ammatorymediatorsininiti- ingalteredsensorynervefunctionindisease. v vi Preface Whilstthe?rstpartfocusesontheclinicaland/orsystemsphysiology,PartIIhas itsfocusatthecellandmolecularlevel. Thisparthighlightsthecurrentundersta- ingofproteins/ionchannels/mediatorsthathavecreatedthemostintenserecent interestintheareaofsensorynervebiology. Together,thesechapterswillgivethe reader important knowledge about how sensory nerve function can be altered pharmacologically. Thelastchapterinthispartdescribestheprocessesthatgive risetoalteredneuralre?exesatthecentrallevel. Themechanismsdescribedin thesechaptersreinforcetheroleofproteins/mediatorshighlightedinthepreceding chapters. Theroleofthesecellular,molecularandphysiologicalprocessesinthe diseasesdiscussedinPart1areemphasized. TheaimofPartIIIistohighlightpotentialdrugtargetsthatmightaltersensory nervefunction. Mostoftheworkhasbeendevotedtothetreatmentofneuropathic painandsothispartheavilyemphasizesthissubject. However,aswillbeapparent fromPartI,manyofthesetargetscouldbeutilizedinothertherapeuticareasthat implicatesensorynervesintheirpathophysiologicalprocesses. Thefocusofthe chaptersisonopioidsandmodulatorsofionchannelsandthenthe?nalchapteris devotedtofuturetreatmentstrategiesforneuropathicpain. Finally,wewouldliketothankallthecontributors,includingco-authors,who agreedtowritechaptersforthisbookandthepublishers,especiallySusanneDathe, fortheirpatienceandassistance. Baltimore B. J. Canning London D. Spina Contents PartI RoleofSensoryNervesinDisease NeuropathicPain:AClinicalPerspective .3 RalfBaron VisceralPain:TheNeurophysiologicalMechanism.31 JyotiN. Sengupta Migraine .75 SilviaBenemei,PaolaNicoletti,JayG. Capone,Francesco DeCesaris,andPierangeloGeppetti AfferentNerveRegulationofBladderFunctioninHealth andDisease .91 WilliamC. deGroatandNaokiYoshimura SensoryNervesandAirwayIrritability.139 B. J. CanningandD. Spina RegulationofCardiacAfferentExcitabilityinIsche. …

Codice articolo 9783540790891

Titolo
Sensory Nerves
Editore
Springer
Anno di pubblicazione
2009
Condizione
New
Rilegatura
Rilegato
Lingua
inglese
ISBN 10
3540790896
ISBN 13
9783540790891
Serie
Libro 21 di 124: Handbook of Experimental Pharmacology

Myboeken BV

Duiven, Paesi Bassi

Venditore con 5 stelle

Venditore AbeBooks dal 14 aprile 2023

Tariffe di spedizione da Paesi Bassi a U.S.A.

ArticoloDa 60 a 60 giorni lavorativiDa 60 a 60 giorni lavorativi
Primo articoloEUR 42,00EUR 61,00
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Myboeken BV is a webshop found in 2012 and based in the Netherlands specialized in English books. Originally, the company was started as a web shop specialized in English educational books. Over time however, Myboeken BV has evolved as a web shop offering books in all kinds of genres. We now have broad offerings in for example cooking books, travelling books, photographic books, children’s books but we also offer anime’s and comic books. Our customers love ordering from us because of our dedication to each and every order. With our small team we make sure that each and every order is handled with care. We take care in our handling and shipping and we take special measurements to ensure quality packing to avoid damages to your books!…

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