Simulation for Designing Clinical Trials: A Pharmacokinetic-pharmacodynamic Modeling Perspective

Kimko, Hui (Editor)/ Duffull, Stephen B. (Editor)

ISBN 10: 0367395606 / ISBN 13: 9780367395605

Editore: CRC Pr I Llc, 2019

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424 pages. 9.25x6.25x1.25 inches. In Stock.

Codice articolo x-0367395606

Dati bibliografici

• Titolo: Simulation for Designing Clinical Trials: A Pharmacokinetic-pharmacodynamic Modeling Perspective
• Editore: CRC Pr I Llc
• Data di pubblicazione: 2019
• Lingua: Inglese
• ISBN 10: 0367395606
• ISBN 13: 9780367395605
• Rilegatura: Paperback
• Condizione: Brand New
• Peso: 1,73 chilogrammi

Descrizione articolo

Riassunto

Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to clinical trial designs according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.

Informazioni sull?autore

Hui C. Kimko, Stephen B. Duffull