Structure-Based Drug Discovery

Jhoti, H. and Leach, A. (eds)

ISBN 10: 1402044062 / ISBN 13: 9781402044069

Editore: Springer, 2007

Riguardo questo articolo

This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,650grams, ISBN:9781402044069.

Codice articolo 9267758

Dati bibliografici

• Titolo: Structure-Based Drug Discovery
• Editore: Springer
• Data di pubblicazione: 2007
• Lingua: Inglese
• ISBN 10: 1402044062
• ISBN 13: 9781402044069
• Rilegatura: Rilegato
• Condizione: Good
• Peso: 650 grammi
• Cataloghi dei venditori:
  • Medicine

Descrizione articolo

Riassunto

This book describes some of the most exciting developments for the discovery of new drugs, such as Fragment-based methods. It contains the latest developments in technologies that can be used to obtain the 3-D structures. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions.

Dalla quarta di copertina

Discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission. Structure-based drug discovery methods have been transformed in the last 5-10 years and are now having a major impact on the discovery of new drugs. Some of the most exciting developments in the field, such as Fragment-based methods, are described in this book.

Structure-based drug discovery describes the latest developments in technologies that can be used to obtain the 3-D structures including the high profile structural genomics approaches being used worldwide. The use of 3-D protein structures in new, Fragment-based, approaches to drug discovery are described in some detail. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions. In addition, developments in computational chemistry methodology are covered together with an assessment of practical applications.

This book is an invaluable resource for medicinal chemists in industry, computational chemists, drug discovery scientists and postgraduates in chemistry or structural biology.