Sucralfate : From Basic Science to the Bedside

G. N. Tytgat

ISBN 10: 1475770197 / ISBN 13: 9781475770193

Editore: Springer US, Springer New York Aug 2013, 2013

Riguardo questo articolo

Druck auf Anfrage Neuware - Printed after ordering - International researchers summarize the current understanding of peptic disease and trace the development of a novel new drug for peptic disease therapy-sucralfate. Contributors present laboratory research along side data from clinical trials as well as from the practice of medicine. Articles discuss the history of sucralfate's development, mechanisms of action, clinical efficacy, and future directions for research. This volume will be of interest to scientists and clinicians working in gastroenterology and gastrointestinal physiology.

Codice articolo 9781475770193

Dati bibliografici

• Titolo: Sucralfate : From Basic Science to the Bedside
• Editore: Springer US, Springer New York Aug 2013
• Data di pubblicazione: 2013
• Lingua: Inglese
• ISBN 10: 1475770197
• ISBN 13: 9781475770193
• Rilegatura: Taschenbuch
• Condizione: Neu
• Dimensioni: 229 L x 152 A x 23 P (millimetri) 229 millimetri di larghezza per 152 millimetri di altezza per 23 millimetri di profondità
• Peso: 594 grammi

Descrizione articolo

Riassunto

International researchers summarize the current understanding of peptic disease and trace the development of a novel new drug for peptic disease therapy-sucralfate. Contributors present laboratory research along side data from clinical trials as well as from the practice of medicine. Articles discuss the history of sucralfate's development, mechanisms of action, clinical efficacy, and future directions for research. This volume will be of interest to scientists and clinicians working in gastroenterology and gastrointestinal physiology.

Contenuti

Introduction; D. Hollander, G.N.J. Tytgat. Pathophysiology of Peptic Ulcer Disease; F. Halter. Decreased Intragastric Acid Concentration as an Approach to Peptic Disease Therapy; A.B.R. Thomson. Strengthening of Mucosal Defenses as an Approach to Peptic Disease Therapy; A.S. Tarnawski. History of the Development of Sucralfate; A. Ishimori. The Chemistry of Sucralfate; K. Ochi. Binding of Bile Acids by Sucralfate; W.F. Caspary. Binding of Sucralfate to the Mucosal Surface; G. Morris. Stimulation of Mucus Production by Sucralfate; C. TasmanJones. Stimulation of Gastroduodenal Bicarbonate Secretion by Sucralfate; D.W. Rees. Effect of Sucrose Octasulphate on Isolated Gastric Cells; M. Lucey, T. Yamada. Effect of Sucralfate of Gastric Surfactant; B.A. Hills. Stimulation of Mucosal Prostaglandins by Sucralfate; D. Rachmilewitz. Effect of Sucralfate on Helicobacter Pylori; J.A. Louw. Sucralfate and Cell Proliferation; H. Kuwayama. Effect of Sucralfate on Vascular Factors: Mucosal Vasoprotection and Angiogenesis; S. Szabo. Sucralfate Effects on Growth Factor Availability; J. Konturek. 16 additional articles. Index.