Synthesis and Characterization Methods of Nanomaterials based Drug Delivery as Cancer Nanotheranostics

Cancer is one of the most common occurring threats to human health. Despite of many advancements and technological development along with several treatment modalities, still cancer is not completely curable. It is adversely affecting the life quality of the patient and contributing in lowering the life expectancy and increasing the economic healthcare burden worldwide. Anomalous physicochemical environment and dysregulated biosynthetic intermediates present inside the tumor microenvironment contribute in regulating cancer cells to evade or defend conventional anti-cancer therapy such as surgery, chemotherapy and radiotherapy. Dynamic behavior of the cancer cells leads to significant loss of drug efficiency that is also somehow associated with several side effects. Conventional anti-cancer therapies also associated with major limitations of side effects and high cost. The latest development in synthesis of tumor microenvironment responsive nanoparticles bargains potential and promising approaches for combating cancers from almost all origins through modulating tumors by initiating acidic and hypoxic microenvironments. To overcome such challenges, nanomedicine approach exploiting the potential of nanoparticles can be a good choice for treatment of such dynamic cancer with limited side effects and ample efficacy.

The purpose of this book is to provide new updates to presently available scientific content related to several synthesis methods of the nanoparticles that have anticancer potential. Besides focusing on new synthesis methods, this book will also focus on the new delivery approach of such nanoparticles along with increasing the stability, efficacy and efficiency of such particles. This book will presents a complete guide covering recent methods of synthesis active nanoparticles and nanomaterials following both traditional and biological approaches. The book will also focus on the isolation, purification and characterization of the newly synthesized nanoparticles and nanomaterials and their application as drug delivery in cancer therapeutics. This book will also explain fundamental methods and approaches with easily understandable explanations, and contains control questions, case studies, equations, and informative tables and schemes to let readers learn faster.

Dr. Alok Raghav, graduated from renowned Faculty of Medicine, Aligarh Muslim University and serving prestigious as research professor at Lee-Gill Ya Cancer and Diabetes Institute, Gachon University, South Korea. Dr Raghav is a distinguished researcher and a known academic person with over a decade in translational research. Prof. Raghav have numerous curtains raising contributions in the field of endocrinology, regenerative medicine, nanomedicine, diabetes management and public health. He has more than 50 peer reviewed international publications and authored multiple book chapters and scientific reviews. Besides, he also delivered numerous talks worldwide in prestigious conferences as invited speaker. Dr. Raghav, holds editorial position with world-renowned peer reviewed journals. He has actively engaged in global health research and policy through joint projects in India and elsewhere. His editorial contribution in this volume demonstrates his strong commitment to interdisciplinary studies and global healthcare issues, especially those accelerated by the COVID-19 pandemic.

Dr. Goo-Bo Jeong, who graduated from a well-known medical school in Korea and is now a Professor, Department of Anatomy and Cell Biology at Gachon University Gill Medical Center, Incheon, Republic of Korea. Prof. Jeong is a renowned academician and respected researcher with profound knowledge in cancer biology, molecular biology, and regenerative medicine. He has authored over 50 peer-reviewed international publications, contributed to several high-impact scientific book chapters and reviews, and edited several books. He has delivered keynote and invited lectures globally in conferences. He provided several keynotes and invited talks globally in conferences. Dr Jeong occupying an editorial and advisory position in several internationally well-known journals and has been engaged in shaping translational research fields in Asia. His stewardship for this book reflects his strong dedication to interdisciplinary partnerships and creative innovation in biomedical sciences, especially in dealing with new global health challenges such as the COVID-19 pandemic.