Targeted Protein Degradation. Questo articolo non è disponibile.Targeted Protein Degradation

Targeted Protein Degradation, Volume 680 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of timely topics, with each. Each written by an international board of authors.

George M. Burslem is currently an Assistant Professor for Biochemistry and Biophysics at the Perelman School of Medicine
Department of Biochemistry and Biophysics and Department of Cancer Biology, University of Pennsylvania. He was previously a Postdoctoral Fellow at Yale University. He completed his PhD. in the University of Leeds, and his MSci in the University of Bristol

Prof. Burslem's lab is interested in developing chemical tools to understand and modulate lysine post-translational modifications, specifically acetylation and ubiquitination. His laboratory is particularly interested in novel pharmacological approaches to modulate post-translational modifications which regulate gene expression and protein stability, employing a multidisciplinary approach including synthetic chemistry, biochemistry, biophysics and cell biology to probe biological systems in cancer biology.