Tight Junctions in Cancer Metastasis

Wen G. Jiang

ISBN 10: 9400760272 / ISBN 13: 9789400760271

Editore: Springer Netherlands, Springer Netherlands Mär 2013, 2013

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Neuware -There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells. The cellular structure is also crucial in drug therapies, namely, the permeability and bioavailability of the drugs, penetration of barriers such as the blood brain barrier. This current volume aims to summarise the current knowledge of tight junctions, their role in cancer and cancer metastasis and is of interest to scientists and clinicians.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 324 pp. Englisch.

Codice articolo 9789400760271

Dati bibliografici

• Titolo: Tight Junctions in Cancer Metastasis
• Editore: Springer Netherlands, Springer Netherlands Mär 2013
• Data di pubblicazione: 2013
• Lingua: Inglese
• ISBN 10: 9400760272
• ISBN 13: 9789400760271
• Rilegatura: Buch
• Condizione: Neu
• Dimensioni: 241 L x 160 A x 23 P (millimetri) 241 millimetri di larghezza per 160 millimetri di altezza per 23 millimetri di profondità
• Peso: 653 grammi

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Riassunto

There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells. The cellular structure is also crucial in drug therapies, namely, the permeability and bioavailability of the drugs, penetration of barriers such as the blood brain barrier. This current volume aims to summarise the current knowledge of tight junctions, their role in cancer and cancer metastasis and is of interest to scientists and clinicians.