Tissue Engineering : Engineering Principles for the Design of Replacement Organs and Tissues

W Mark Saltzman

ISBN 10: 019514130X / ISBN 13: 9780195141306

Editore: Oxford University Press Jul 2004, 2004

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Neuware - Tissue or organ transplantation are among the few options available for patients with excessive skin loss, heart or liver failure, and many common ailments, and the demand for replacement tissue greatly exceeds the supply, even before one considers the serious constraints of immunological tissue type matching to avoid immune rejection. Tissue engineering promises to help sidestep constraints on availability and overcome the scientific challenges, with huge medical benefits. This book lays out the principles of tissue engineering. It will be a useful reference work for those associated with this field and as a textbook for specialized courses in the subject. It is a companion volume to Saltzman's OUP book on drug delivery. Codice articolo 9780195141306

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Titolo: Tissue Engineering : Engineering Principles ...

Casa editrice: Oxford University Press Jul 2004

Data di pubblicazione: 2004

Legatura: Buch

Condizione: Neu

Descrizione articolo

Riassunto:

Tissue engineering is a new field of biomedical engineering, in which synthetic materials are used together with biological components such as tissue fragments, cells, proteins to encourage tissue regeneration, regrowth, and repair. This book introduces the principles of tissue engineering in a unique way that is ideally suited for the modern engineering student. A review of developmental biology is presented early in the book, since biological development is the fundamental process of most relevance for tissue engineering. The study of development provides a pathway to basic bioengineering units on cell adhesion, migration, assembly, and transport, which are integrated in the final sections of the book into tissue engineering processes (such as cell delivery, growth factor administration, and polymeric scaffold materials).

Contenuti:

• Part 1: Tissue Exchange and Tissue Development
• 1: The State-of-the-Art in Tissue Exchange
• 2: Objectives of Tissue Engineering
• 3: Elements of Tissue Development
• Part 2: Tissue Engineering Fundamentals
• 4: Cell Growth and Differentiation
• 5: Cell and Tissue Mechanics
• 6: Cell Adhesion
• 7: Cell Migration
• 8: Cell Aggregation and Tissue Equivalents
• 9: Tissue Barriers to Molecular and Cellular Transport
• Part 3: Tissue Engineering Practice
• 10: Cell Delivery and Recirculation
• 11: Delivery of Molecular Agents in Tissue Engineering
• 12: Cell Interactions With Polymers
• 13: Approaches to Tissue Engineering
• 14: Case Studies in Tissue Engineering
• Appendices
• A. Introduction to Polymers
• B. Analysis of Molecular Transport
• C. Useful Data
• D. Nomenclature and Abbreviations