Toll-like Receptors: Roles in Infection and Neuropathology (Current Topics in Microbiology and Immunology)

Lingua: inglese

Editore: U.S.A.: Springer, 2009

3642005489 / 9783642005480

Serie: Libro 50 di 322 - Current Topics in Microbiology and Immunology

Da: Masalai Press, Oakland, CA, U.S.A.Masalai Press

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191 pp., illustrations, bibliography, index. Mammalian Toll-like receptors (TLRs) were first identified in 1997 based on their homology with Drosophila Toll, which mediates innate immunity in the fly. In recent years, the number of studies describing TLR expression and function in the nervous system has been increasing steadily and expanding beyond their traditional roles in infectious diseases to neurodegenerative disorders and injury. Interest in the field serves as the impetus for this volume in the Current Topics in Microbiology and Immunology series entitled "Toll-like receptors: Roles in Infection and Neuropathology". The first five chapters highlight more traditional roles for TLRs in infectious diseases of the CNS. The second half of the volume discusses recently emerging roles for TLRs in non-infectious neurodegenerative diseases and the challenges faced in these models with identifying endogenous ligands. Several conceptual theories are introduced in various chapters that deal with the dual nature of TLR engagement and whether these signals favor neuroprotective versus neurodegenerative outcomes. This volume should be informative for both experts as well as newcomers to the field of TLRs in the nervous system based on its coverage of basic TLR biology as well as specialization to discuss specific diseases of the nervous system where TLR function has been implicated. A must read for researchers interested in the dual role of these receptors in neuroinfection and neurodegeneration.

Codice articolo 3642005489EVANS100915

Titolo
Toll-like Receptors: Roles in Infection and Neuropathology (Current Topics in Microbiology and Immunology)
Autore
Kielian, Tammy (Editor)
Editore
U.S.A.: Springer
Anno di pubblicazione
2009
Condizione
Very Good
Rilegatura
Hardcover
Lingua
inglese
ISBN 10
3642005489
ISBN 13
9783642005480
Serie
Libro 50 di 322: Current Topics in Microbiology and Immunology

Masalai Press

Oakland, CA, U.S.A.

Venditore con 5 stelle

Venditore AbeBooks dal 28 dicembre 2011

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ArticoloDa 5 a 14 giorni lavorativiDa 2 a 4 giorni lavorativi
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Masalai Press has been selling books on the internet since 2000, and has been involved in book selling since 1985. Customer service and accurate descriptions are a priority. Masalai Press specializes in books about the Pacific Islands, especially Papua New Guinea. Masalai Press is the regional representative of the University of Papua New Guinea Press, and has been co-publishing with the UPNG Press since 2008.

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Papua New Guinea, Pacific Islands, Asia, Linguistics, Foreign Language Dictionaries, Sciences

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Masalai Press

CA, U.S.A.