Paperback. Advances in bioinformatics and systems biology require improved computational methods for analyzing data, while progress in molecular biology is in turn influencing the development of computer science methods. This book introduces some key problems in bioinformatics, discusses the models used to formally describe these problems, and analyzes the algorithmic approaches used to solve them. After introducing the basics of molecular biology and algorithmics, Part I explains string algorithms and alignments; Part II details the field of physical mapping and DNA sequencing; and Part III examines the application of algorithmics to the analysis of biological data. Exciting application examples include predicting the spatial structure of proteins, and computing haplotypes from genotype data. This book describes topics in detail and presents formal models in a mathematically precise, yet intuitive manner, with many figures and chapter summaries, detailed derivations, and examples. It is well suited as an introduction into the field of bioinformatics, and will benefit students and lecturers in bioinformatics and algorithmics, while also offering practitioners an update on current research topics. Advances in bioinformatics and systems biology require improved computational methods for analyzing data, while progress in molecular biology is in turn influencing the development of computer science methods. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

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Titolo: Algorithmic Aspects of Bioinformatics (Paperback)
Editore: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, Berlin
Data di pubblicazione: 2010
Lingua: Inglese
ISBN 10: 3642091008
ISBN 13: 9783642091001
Rilegatura: Paperback
Edizione: prima edizione
Condizione: new

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This book introduces some key problems in bioinformatics, discusses the models used to formally describe these problems, and analyzes the algorithmic approaches used to solve them. After introducing the basics of molecular biology and algorithmics, the book explains string algorithms and alignments. It next details the field of physical mapping and DNA sequencing and examines the application of algorithmics to the analysis of biological data. The book features exciting application examples, such as predicting the spatial structure of proteins, and computing haplotypes from genotype data. This book describes topics in detail and presents formal models in a mathematically precise, yet intuitive manner, with many figures and chapter summaries, detailed derivations, and examples. It is well suited as an introduction into the field of bioinformatics, and will benefit students and lecturers in bioinformatics and algorithmics, while also offering practitioners an update on current researchtopics.

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