An Introduction to Randomized Controlled Clinical Trials

Matthews, J. N. S.

ISBN 10: 0340761431 / ISBN 13: 9780340761434

Editore: Hachette Learning, 2000

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Ships from the UK. Used book that is in clean, average condition without any missing pages. Codice articolo 11859951-75

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Titolo: An Introduction to Randomized Controlled ...

Casa editrice: Hachette Learning

Data di pubblicazione: 2000

Legatura: Brossura

Condizione: Good

Edizione: 1st.

Descrizione articolo

Riassunto:

Evidence from randomized controlled clinical trials is now widely accepted as the only sound basis for assessing the efficacy of new treatments. Since the inception of modern trials in the 1940's, their use and the associated methodology has grown rapidly, and there in now a considerable body of knowledge that must now be assimilated by anyone studying the subject. Statisticians have been amongst the foremost contributors to this methodology, with medical statisticians being involved in the conduct of numerous trials. This important new book provides undergraduates, masters students and researcher with a concise introduction to the principles used in this area. It introduces readers to the concepts behind randomization methods and their analysis, and includes chapters on meta-analysis and specialized designs, such as cluster-randomization trails, crossover trials and equivalence studies. It assumes no underlying medical background and material from each chapter is illustrated with problems and real-life examples.

Recensione:

This is a very useful introduction to clinical trials. (Biometrics)

The textbook seems to be a good supply for undergraduate or master students in the medical or statistics sciences and gives researchers a good introduction into the field of randomized controlled clinical trials. (Zentralblatt MATH)

...invaluable as a handy (and inexpensive) reminder of the basics for the experienced statistician. Junior statisticians who have absorbed its contents will be ready to start provision of competent technical support for clinical trials, whether within the pharmaceutical industry or in academic environments. (Transactions)

The target audience includes undergraduate and postgraduate students of statistics, as well as applied statisticians working in industry, government or research organizations. Overall, this is a well written book. (Statistics in Medicine, Vol 20)

I found much wisdom in this book about the role and value of statistical methods in randomized controlled trials. Likewise regarding their influence on decisions based on trial evidence- in particular, that this is more limited than the anticipated readership might believe. (International Journal of Epidemiology)

...well written and easy to read. (Short Book Reviews (International Statistical Inst)