Ariane herrick (54 risultati)
Orthopaedics and Rheumatology in Focus
Andrew, J. Glynne, Hutchinson, Charles, Herrick, Ariane L., Funk, Len
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Da: Better World Books Ltd, Dunfermline, Regno UnitoBetter World Books Ltd
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EUR 5,62
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Condizione: Good. 1st Edition. Former library copy. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.
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- Prima edizione
Da: Better World Books Ltd, Dunfermline, Regno UnitoBetter World Books Ltd
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Buono
EUR 5,62
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Condizione: Good. 1st Edition. Former library copy. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.
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Da: Phatpocket Limited, Waltham Abbey, HERTS, Regno UnitoPhatpocket Limited
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EUR 1,44
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Condizione: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.
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Da: PBShop.store UK, Fairford, GLOS, Regno UnitoPBShop.store UK
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EUR 144,27
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HRD. Condizione: New. New Book. Shipped from UK. Established seller since 2000.
Raynaud?s Phenomenon : From Pathogenesis to Management
Wigley, Fredrick M. (EDT); Herrick, Ariane L. (EDT); Flavahan, Nicholas A. (EDT)
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Da: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
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EUR 150,24
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Condizione: New.
Raynaud?s Phenomenon : From Pathogenesis to Management
Wigley, Fredrick M. (EDT); Herrick, Ariane L. (EDT); Flavahan, Nicholas A. (EDT)
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Da: GreatBookPricesUK, Woodford Green, Regno UnitoGreatBookPricesUK
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EUR 144,26
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Condizione: New.
Raynaud?s Phenomenon : From Pathogenesis to Management
Wigley, Fredrick M. (EDT); Herrick, Ariane L. (EDT); Flavahan, Nicholas A. (EDT)
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Da: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
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EUR 165,83
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Condizione: As New. Unread book in perfect condition.
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Da: Speedyhen, Hertfordshire, Regno UnitoSpeedyhen
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EUR 127,82
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Condizione: NEW.
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Da: preigu, Osnabrück, Germaniapreigu
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EUR 104,20
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Taschenbuch. Condizione: Neu. Raynaud's Phenomenon | A Guide to Pathogenesis and Treatment | Fredrick M. Wigley (u. a.) | Taschenbuch | xix | Englisch | 2016 | Springer | EAN 9781493947249 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | An…bieter: preigu.
Nailfold Capillaroscopy in Rheumatological Diseases
Herrick, Ariane L. (EDT); Murray, Andrea (EDT); Taylor, Chris (EDT); Smith, Vanessa (EDT); Cutolo, Maurizio (EDT)
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Da: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
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EUR 178,32
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Condizione: New.
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Da: Grand Eagle Retail, Bensenville, IL, U.S.A.Grand Eagle Retail
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EUR 180,70
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Hardcover. Condizione: new. Hardcover. Nailfold capillaroscopy allows non-invasive assessment of the finger microvasculature. At the nailfold, capillaries run parallel rather than perpendicular to the skin surface, allowing their structure to be visualised under magnification.The main clinical indication for nailfold capillarosc…opy is the assessment of the patient with Raynauds phenomenon (RP). Normal nailfold capillaries are reassuring, consistent with primary (benign) RP, whereas abnormal capillaries (dilated capillaries, reduced capillary density) raise suspicion of an underlying systemic sclerosis-spectrum disorder. Although the significance of abnormal nailfold capillaries was recognised over 50 years ago, only within the last 20 years has there been a surge of interest in capillaroscopy, fuelled by the recognition that abnormal nailfold capillaries are an independent risk factor for development of systemic sclerosis and by abnormal nailfold capillaries being included in the 2013 classification criteria for systemic sclerosis. The increased interest in nailfold capillaroscopy is evidenced by capillaroscopy courses of the British Society for Rheumatology and of EULAR being over-subscribed.This textbook is aimed primarily at rheumatologists diagnosing connective tissue disease (i.e. the majority of rheumatologists) and who undertake/wish to undertake nailfold capillaroscopy. The book is also of interest to scientists with an interest in the microvasculature. It provides an authoritative guide which allows the reader to feel confident in their clinical practice, and to understand the background to nailfold capillaroscopy and its ongoing potential. Topics discussed include the indications for nailfold capillaroscopy, how to acquire and interpret images (including the different methodologies), capillary abnormalities found in different connective tissue diseases (especially systemic sclerosis and dermatomyositis), progress in quantitative and automated analyses, and capillaroscopic research. Finally, a series of case histories is presented to put into context the role of capillaroscopy in diagnosis and in predicting risk. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
Raynaud?s Phenomenon : From Pathogenesis to Management
Wigley, Fredrick M. (EDT); Herrick, Ariane L. (EDT); Flavahan, Nicholas A. (EDT)
- Rilegato
Da: GreatBookPricesUK, Woodford Green, Regno UnitoGreatBookPricesUK
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EUR 168,00
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Condizione: As New. Unread book in perfect condition.
Nailfold Capillaroscopy in Rheumatological Diseases
Herrick, Ariane L. (EDT); Murray, Andrea (EDT); Taylor, Chris (EDT); Smith, Vanessa (EDT); Cutolo, Maurizio (EDT)
- Rilegato
Da: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Come nuovo
EUR 185,85
EUR 2,30 spedizioneSpedito in U.S.A.Quantità: 2 disponibili
Condizione: As New. Unread book in perfect condition.
- Brossura
Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 125,24
EUR 64,37 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Raynaud's Phenomenon: A Guide to Pathogenesis and Treatment comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists alike. In the last decade, there have been important advances n…ot only in understanding the pathophysiology of Raynaud's Phenomenon (RP), but also in developing diagnostic methods and effective drug and non-drug therapies. Thoroughly discussing the various manifestations of RP, including childhood RP, RP secondary to connective tissue disease, and a variety of other associated disorders that include vascular perturbation that mimics RP, this title provides a wealth of new information available on normal and abnormal thermoregulation and helps physicians identify the best therapeutic approaches to treating RP. The work offers differential diagnosis options, reviews potential causes such as autoimmune disease, industrial trauma, drugs, and metabolic causes and provides clear recommendations for therapy. Engaging readers with case vignettes and a plethora of visual aids, Raynaud's Phenomenon: A Guide to Pathogenesis and Treatment is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to physicians, patients, and individuals dealing with these disease processes.
- Brossura
Da: Books Puddle, New York, NY, U.S.A.Books Puddle
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EUR 192,03
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Condizione: New.
- Brossura
Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 134,63
EUR 64,85 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists. Raynaud's phenomenon is an inappropriate and exaggerated response of the digital and cutaneous circulation to co…ld environmental temperatures. It is common, often causing significant morbidity and it is a major challenge for physicians at every level and specialty. A comprehensive review of Raynaud's is now timely because of the incredible progress in understanding the molecular mechanisms of the normal regulation of cutaneous blood flow and how disease can disrupt the function of these specialized vessels. Likewise, the clinical implications of Raynaud's phenomenonare better appreciated with studies defining its prevalence, the associated diseases, and new treatment approaches for patients suffering from it. The nomenclature used to classify cases has changed over the years and is important to understand these terms both for clinical care andresearch.This fully updated second edition comprehensively discusses various causes of Raynaud's phenomenonincluding childhood Raynaud's phenomenon, Raynaud's phenomenonsecondary to connective tissue disease, occupational causes, and a variety of other associated disorders.Careful consideration is given to the diagnosis of Raynaud's phenomenon with state of the art discussionof nailfold capillary examination, non-invasive imaging, angiography, and appropriate serological testing. The concept that Raynaud's phenomenonis associated with systemic disease or can be the manifestation of a systemic vasospastic disorder is also presented. In addition to reviewing both non-drug and drug therapy for patients with Raynaud's phenomenon, this volume provides a practical approach in specific clinical situations by presenting problematic cases and the authors' expert opinions on therapy.It also discusses mechanisms contributing to the vascular dysfunctionof primary Raynaud's phenomenon and the vascular disease of secondary Raynaud's phenomenon.Engaging readers with case vignettes and a plethora of visual aids, Raynaud's Phenomenon: From Pathogenesis to Management is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to adult and pediatric physicians, rheumatologists, and clinical and basic researchers.
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Da: Grand Eagle Retail, Bensenville, IL, U.S.A.Grand Eagle Retail
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 206,06
Spedizione gratuitaSpedito in U.S.A.Quantità: 1 disponibili
Hardcover. Condizione: new. Hardcover. This book comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists. Raynauds phenomenon is an inappropriate and exaggerated response of the digital and cutaneous circulation to cold environmental temperatures. It is common,…often causing significant morbidity and it is a major challenge for physicians at every level and specialty. A comprehensive review of Raynauds is now timely because of the incredible progress in understanding the molecular mechanisms of the normal regulation of cutaneous blood flow and how disease can disrupt the function of these specialized vessels. Likewise, the clinical implications of Raynauds phenomenon are better appreciated with studies defining its prevalence, the associated diseases, and new treatment approaches for patients suffering from it. The nomenclature used to classify cases has changed over the years and is important to understand these terms both for clinical care andresearch.This fully updated second edition comprehensively discusses various causes of Raynauds phenomenon including childhood Raynauds phenomenon, Raynauds phenomenon secondary to connective tissue disease, occupational causes, and a variety of other associated disorders. Careful consideration is given to the diagnosis of Raynauds phenomenon with state of the art discussion of nailfold capillary examination, non-invasive imaging, angiography, and appropriate serological testing. The concept that Raynauds phenomenon is associated with systemic disease or can be the manifestation of a systemic vasospastic disorder is also presented. In addition to reviewing both non-drug and drug therapy for patients with Raynauds phenomenon, this volume provides a practical approach in specific clinical situations by presenting problematic cases and the authors expert opinions on therapy. It also discusses mechanisms contributing to the vascular dysfunctionof primary Raynauds phenomenon and the vascular disease of secondary Raynauds phenomenon.Engaging readers with case vignettes and a plethora of visual aids, Raynauds Phenomenon: From Pathogenesis to Management is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to adult and pediatric physicians, rheumatologists, and clinical and basic researchers. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
Raynaud's Phenomenon: A Guide to Pathogenesis and Treatment
Wigley, Fredrick M. (Editor) / Herrick, Ariane L. (Editor) / Flavahan, Nicholas A. (Editor)
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Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 196,60
EUR 14,76 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 1 disponibili
Paperback. Condizione: Brand New. reprint edition. 413 pages. 10.00x7.00x0.94 inches. In Stock.
Raynaud's Phenomenon: From Pathogenesis to Management
Wigley, Fredrick M. (Editor)/ Herrick, Ariane L. (Editor)/ Flavahan, Nicholas A. (Editor)
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Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 193,95
EUR 17,71 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 1 disponibili
Hardcover. Condizione: Brand New. 2nd edition. 460 pages. 10.01x7.01x10.10 inches. In Stock.
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Da: Rarewaves.com USA, London, LONDO, Regno UnitoRarewaves.com USA
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 211,69
Spedizione gratuitaSpedito da Regno Unito a U.S.A.Quantità: 1 disponibili
Hardback. Condizione: New. Second Edition 2024. This book comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists. Raynaud's phenomenon is an inappropriate and exaggerated response of the digital and cutaneous circulation to cold environmental temperatures. It i…s common, often causing significant morbidity and it is a major challenge for physicians at every level and specialty. A comprehensive review of Raynaud's is now timely because of the incredible progress in understanding the molecular mechanisms of the normal regulation of cutaneous blood flow and how disease can disrupt the function of these specialized vessels. Likewise, the clinical implications of Raynaud's phenomenon are better appreciated with studies defining its prevalence, the associated diseases, and new treatment approaches for patients suffering from it. The nomenclature used to classify cases has changed over the years and is important to understand these terms both for clinical care andresearch.This fully updated second edition comprehensively discusses various causes of Raynaud's phenomenon including childhood Raynaud's phenomenon, Raynaud's phenomenon secondary to connective tissue disease, occupational causes, and a variety of other associated disorders. Careful consideration is given to the diagnosis of Raynaud's phenomenon with state of the art discussion of nailfold capillary examination, non-invasive imaging, angiography, and appropriate serological testing. The concept that Raynaud's phenomenon is associated with systemic disease or can be the manifestation of a systemic vasospastic disorder is also presented. In addition to reviewing both non-drug and drug therapy for patients with Raynaud's phenomenon, this volume provides a practical approach in specific clinical situations by presenting problematic cases and the authors' expert opinions on therapy. It also discusses mechanisms contributing to the vascular dysfunctionof primary Raynaud's phenomenon and the vascular disease of secondary Raynaud's phenomenon.Engaging readers with case vignettes and a plethora of visual aids, Raynaud's Phenomenon: From Pathogenesis to Management is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to adult and pediatric physicians, rheumatologists, and clinical and basic researchers.
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Da: moluna, Greven, Germaniamoluna
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 165,97
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Condizione: New.
- Rilegato
Da: Buchpark, Trebbin, GermaniaBuchpark
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Ottimo
EUR 108,79
EUR 105,00 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Condizione: Sehr gut. Zustand: Sehr gut | Seiten: 464 | Sprache: Englisch | Produktart: Bücher | This book comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists. Raynaud¿s phenomenon is an inappropriate and exaggerated response of the digital and cutaneous cir…culation to cold environmental temperatures. It is common, often causing significant morbidity and it is a major challenge for physicians at every level and specialty. A comprehensive review of Raynaud¿s is now timely because of the incredible progress in understanding the molecular mechanisms of the normal regulation of cutaneous blood flow and how disease can disrupt the function of these specialized vessels. Likewise, the clinical implications of Raynaud¿s phenomenon are better appreciated with studies defining its prevalence, the associated diseases, and new treatment approaches for patients suffering from it. The nomenclature used to classify cases has changed over the years and is important to understand these terms both for clinical care andresearch.This fully updated second edition comprehensively discusses various causes of Raynaud¿s phenomenon including childhood Raynaud¿s phenomenon, Raynaud¿s phenomenon secondary to connective tissue disease, occupational causes, and a variety of other associated disorders. Careful consideration is given to the diagnosis of Raynaud¿s phenomenon with state of the art discussion of nailfold capillary examination, non-invasive imaging, angiography, and appropriate serological testing. The concept that Raynaud¿s phenomenon is associated with systemic disease or can be the manifestation of a systemic vasospastic disorder is also presented. In addition to reviewing both non-drug and drug therapy for patients with Raynaud¿s phenomenon, this volume provides a practical approach in specific clinical situations by presenting problematic cases and the authors¿ expert opinions on therapy. It also discusses mechanisms contributing to the vascular dysfunctionof primary Raynaud¿s phenomenon and the vascular disease of secondary Raynaud¿s phenomenon.Engaging readers with case vignettes and a plethora of visual aids, Raynaud¿s Phenomenon: From Pathogenesis to Management is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to adult and pediatric physicians, rheumatologists, and clinical and basic researchers.
- Rilegato
Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 153,90
EUR 63,28 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Nailfold capillaroscopy allows non-invasive assessment of the finger microvasculature. At the nailfold, capillaries run parallel rather than perpendicular to the skin surface, allowing their structure to be visualised under magnification.The main clinica…l indication for nailfold capillaroscopy is the assessment of the patient with Raynaud s phenomenon (RP). Normal nailfold capillaries are reassuring, consistent with primary ( benign ) RP, whereas abnormal capillaries (dilated capillaries, reduced capillary density) raise suspicion of an underlying systemic sclerosis-spectrum disorder. Although the significance of abnormal nailfold capillaries was recognised over 50 years ago, only within the last 20 years has there been a surge of interest in capillaroscopy, fuelled by the recognition that abnormal nailfold capillaries are an independent risk factor for development of systemic sclerosis and by abnormal nailfold capillaries being included in the 2013 classification criteria for systemic sclerosis. The increased interest in nailfold capillaroscopy is evidenced by capillaroscopy courses of the British Society for Rheumatology and of EULAR being over-subscribed.This textbook is aimed primarily at rheumatologists diagnosing connective tissue disease (i.e. the majority of rheumatologists) and who undertake/wish to undertake nailfold capillaroscopy. The book is also of interest to scientists with an interest in the microvasculature. It provides an authoritative guide which allows the reader to feel confident in their clinical practice, and to understand the background to nailfold capillaroscopy and its ongoing potential. Topics discussed include the indications for nailfold capillaroscopy, how to acquire and interpret images (including the different methodologies), capillary abnormalities found in different connective tissue diseases (especially systemic sclerosis and dermatomyositis), progress in quantitative and automated analyses, and capillaroscopic research. Finally, a series of case histories is presented to put into context the role of capillaroscopy in diagnosis and in predicting risk.
Raynaud's Phenomenon: A Guide to Pathogenesis and Treatment Wigley, Fredrick M.; Herrick, Ariane L. and Flavahan, Nicholas A.
Wigley, Fredrick M.; Herrick, Ariane L. and Flavahan, Nicholas A.
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Da: BUCHSERVICE / ANTIQUARIAT Lars Lutzer, Wahlstedt, GermaniaBUCHSERVICE / ANTIQUARIAT Lars Lutzer
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Molto buono
EUR 179,95
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Condizione: gut. Raynaud's Phenomenon: A Guide to Pathogenesis and Treatment In englischer Sprache. pages.
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Da: Books Puddle, New York, NY, U.S.A.Books Puddle
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EUR 226,93
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Condizione: New.
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Da: Books Puddle, New York, NY, U.S.A.Books Puddle
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EUR 233,73
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Condizione: New. 2nd ed. 2024 edition NO-PA16APR2015-KAP.
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Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
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EUR 226,93
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Hardcover. Condizione: Brand New. 200 pages. 9.26x6.11x9.49 inches. In Stock.
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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EUR 171,19
EUR 65,84 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists. Raynaud's phenomenon is an inappropriate and exaggerated response of the digital and cutaneous circulation to cold envi…ronmental temperatures. It is common, often causing significant morbidity and it is a major challenge for physicians at every level and specialty. A comprehensive review of Raynaud's is now timely because of the incredible progress in understanding the molecular mechanisms of the normal regulation of cutaneous blood flow and how disease can disrupt the function of these specialized vessels. Likewise, the clinical implications of Raynaud's phenomenonare better appreciated with studies defining its prevalence, the associated diseases, and new treatment approaches for patients suffering from it. The nomenclature used to classify cases has changed over the years and is important to understand these terms both for clinical care andresearch.This fully updated second edition comprehensively discusses various causes of Raynaud's phenomenonincluding childhood Raynaud's phenomenon, Raynaud's phenomenonsecondary to connective tissue disease, occupational causes, and a variety of other associated disorders.Careful consideration is given to the diagnosis of Raynaud's phenomenon with state of the art discussionof nailfold capillary examination, non-invasive imaging, angiography, and appropriate serological testing. The concept that Raynaud's phenomenonis associated with systemic disease or can be the manifestation of a systemic vasospastic disorder is also presented. In addition to reviewing both non-drug and drug therapy for patients with Raynaud's phenomenon, this volume provides a practical approach in specific clinical situations by presenting problematic cases and the authors' expert opinions on therapy.It also discusses mechanisms contributing to the vascular dysfunctionof primary Raynaud's phenomenon and the vascular disease of secondary Raynaud's phenomenon.Engaging readers with case vignettes and a plethora of visual aids, Raynaud's Phenomenon: From Pathogenesis to Management is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to adult and pediatric physicians, rheumatologists, and clinical and basic researchers.
Raynaud's Phenomenon: From Pathogenesis to Management
Wigley, Fredrick M. (Editor)/ Herrick, Ariane L. (Editor)/ Flavahan, Nicholas A. (Editor)
- Rilegato
Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 260,61
EUR 17,71 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 1 disponibili
Hardcover. Condizione: Brand New. 2nd edition. 460 pages. 10.01x7.01x10.10 inches. In Stock.
- Rilegato
Da: Rarewaves.com UK, London, Regno UnitoRarewaves.com UK
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 202,94
EUR 76,73 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 1 disponibili
Hardback. Condizione: New. Second Edition 2024. This book comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists. Raynaud's phenomenon is an inappropriate and exaggerated response of the digital and cutaneous circulation to cold environmental temperatures. It i…s common, often causing significant morbidity and it is a major challenge for physicians at every level and specialty. A comprehensive review of Raynaud's is now timely because of the incredible progress in understanding the molecular mechanisms of the normal regulation of cutaneous blood flow and how disease can disrupt the function of these specialized vessels. Likewise, the clinical implications of Raynaud's phenomenon are better appreciated with studies defining its prevalence, the associated diseases, and new treatment approaches for patients suffering from it. The nomenclature used to classify cases has changed over the years and is important to understand these terms both for clinical care andresearch.This fully updated second edition comprehensively discusses various causes of Raynaud's phenomenon including childhood Raynaud's phenomenon, Raynaud's phenomenon secondary to connective tissue disease, occupational causes, and a variety of other associated disorders. Careful consideration is given to the diagnosis of Raynaud's phenomenon with state of the art discussion of nailfold capillary examination, non-invasive imaging, angiography, and appropriate serological testing. The concept that Raynaud's phenomenon is associated with systemic disease or can be the manifestation of a systemic vasospastic disorder is also presented. In addition to reviewing both non-drug and drug therapy for patients with Raynaud's phenomenon, this volume provides a practical approach in specific clinical situations by presenting problematic cases and the authors' expert opinions on therapy. It also discusses mechanisms contributing to the vascular dysfunctionof primary Raynaud's phenomenon and the vascular disease of secondary Raynaud's phenomenon.Engaging readers with case vignettes and a plethora of visual aids, Raynaud's Phenomenon: From Pathogenesis to Management is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to adult and pediatric physicians, rheumatologists, and clinical and basic researchers.
