Kellum john m d (36 risultati)

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Condizione: New. Offers a comprehensive and in-depth understanding of endotoxin in critical illness, covering historical perspectives, molecular intricacies, physiological basis of disease, and evolutionary aspectsEmphasizes the clinical relevance of endoto.

Taschenbuch. Condizione: Neu. Neuware - Endotoxin in Critical Illness intricately explores the theme of endotoxin and sepsis through the lenses of basic, clinical, and translational science. This work consolidates and synthesizes novel clinical insights and groundbreaking scientific discoveries into one comprehensive resource on endotoxic septic shock and sheds light on cutting-edge approaches in treatment. Beginning with a historical journey, the book traces the evolution of understanding from ancient concepts to modern molecular insights. It covers the physiological aspects of endotoxin sensitivity, tolerance, and human response variation. The crucial role of the gut microbiome in critical illness serves as a translational link between foundational science and clinical implications, and the complex language of bacterial communication is introduced, merging basic science with potential translational applications. In the clinical arena, chapters cover the critical role of endotoxin in septic shock, trauma, and its relevance in COVID-19, providing a translational bridge between laboratory findings and real-world clinical scenarios. The historical context of anti-endotoxin drug development is revisited, emphasizing the translational challenges faced in bridging basic science discoveries to clinical applications. The discussion on quantifying endotoxin concentration as well as the exploration of therapeutic rationale and clinical experiences with endotoxin removal therapy serve as a culmination of basic understanding translated into practical applications. The book concludes by contemplating the complexity of sepsis and acknowledging the challenges in achieving personalized medicine and underscoring the dynamic nature of the translational journey. In essence, this comprehensive exploration provides clinicians, researchers, and scientists with a holistic understanding of endotoxin and sepsis and potential advancements in patient care.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Everyone in America has or will interact with our healthcare system in one way or another, and this book details the ways in which hospital systems are now working to reduce costs by reducing care--often at the expense of patient interests. New 'value-based' models, widely embraced by industry and policymakers alike, actually increase this risk. Fortunately, there are ways in which patients, all of us, can reduce our risk and improve our care. The US is moving rapidly in an uncharted direction that is unlike anything we've ever seen before in the US or anywhere in the world. Code Green: How the BIG LIE in Healthcare Affects Us All lays out the problems we are facing, the history that led us here, the reasons policymakers and hospital executives are enamored with the proposed solutions, and the reasons they are unlikely to benefit patients. Also discussed are comparisons with other systems in other countries and potential solutions both at the policy level and for individual patients who will be forced to endure the next several years of turmoil. Finally, practical advice for patients is provided throughout the book.…