Wei wenyi (33 risultati)
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Da: Books Puddle, New York, NY, U.S.A.Books Puddle
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This SpringerBrief explores the physiological roles of Skp1-Cullin1-F-box Complex (SCF) and Anaphase Promoting Complex (APC) in normal cells and in tumor formation. These two related, multi-subunit E3 ubiquitin ligase enzymes, APC and SCF are thou…ght to be the major driving forces governing proper cell cycle progression. Defective cell cycle regulation leads to genomic instability and ultimately, cancer development. Selective degradation of key cell cycle regulators by the ubiquitin-proteasome system has been proven to be a major regulatory mechanism for ensuring ordered and coordinated cell cycle progression. The SCF and APC E3 ligases have been characterized to play pivotal roles in regulating the cell cycle progression by timely degrading various critical cell cycle regulators. This Brief reviews recent studies that have shown that deregulation of signaling pathways in which the two ubiquitin ligases are involved causes aberrant cell cycle regulation, in turn leading to tumorigenesis. The text also discusses how SCF and APC may present promising therapeutic targets to treat various cancers.
Lingua: Inglese
Editore: Springer, 2021
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: Ria Christie Collections, Uxbridge, Regno UnitoRia Christie Collections
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Lingua: Inglese
Editore: Springer, 2020
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: Ria Christie Collections, Uxbridge, Regno UnitoRia Christie Collections
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Editore: Springer, 2020
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: GreatBookPricesUK, Woodford Green, Regno UnitoGreatBookPricesUK
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Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
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Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
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Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: GreatBookPricesUK, Woodford Green, Regno UnitoGreatBookPricesUK
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Altre immaginiLingua: Inglese
Editore: Springer, 2021
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: preigu, Osnabrück, Germaniapreigu
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Taschenbuch. Condizione: Neu. Cullin-RING Ligases and Protein Neddylation | Biology and Therapeutics | Yi Sun (u. a.) | Taschenbuch | Advances in Experimental Medicine and Biology | viii | Englisch | 2021 | Springer | EAN 9789811510274 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg…, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Lingua: Inglese
Editore: Springer, 2021
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: Books Puddle, New York, NY, U.S.A.Books Puddle
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EUR 215,49
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Condizione: New. 1st ed. 2020 edition NO-PA16APR2015-KAP.
Lingua: Inglese
Editore: Springer, 2020
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: Books Puddle, New York, NY, U.S.A.Books Puddle
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Condizione: New. pp. VIII, 372 119 illus., 68 illus. in color. 1st ed. 2020 edition NO-PA16APR2015-KAP.
Lingua: Inglese
Editore: Springer Nature Singapore, Springer Nature Singapore, 2020
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are activated…by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine.
Lingua: Inglese
Editore: Springer, Springer, 2021
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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EUR 168,73
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are act…ivated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine.
Cullin-ring Ligases and Protein Neddylation: Biology and Therapeutics
Sun, Yi (Editor)/ Wei, Wenyi (Editor)/ Jin, Jianping (Editor)
Lingua: Inglese
Editore: Springer Nature, 2021
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
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Paperback. Condizione: Brand New. 380 pages. 10.00x7.01x0.90 inches. In Stock.
Cullin-ring Ligases and Protein Neddylation: Biology and Therapeutics
Sun, Yi (Editor)/ Wei, Wenyi (Editor)/ Jin, Jianping (Editor)
Lingua: Inglese
Editore: Springer Verlag, 2020
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
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EUR 241,20
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Hardcover. Condizione: Brand New. 382 pages. 10.00x7.00x1.10 inches. In Stock.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This SpringerBrief explores the physiological roles of Skp1-Cullin1-F-box Complex (SCF) and Anaphase Promoting Complex (APC) in normal cells and in tumor formation. These two related, multi-subunit E3 ubiquitin ligase enzymes, APC…and SCF are thought to be the major driving forces governing proper cell cycle progression. Defective cell cycle regulation leads to genomic instability and ultimately, cancer development. Selective degradation of key cell cycle regulators by the ubiquitin-proteasome system has been proven to be a major regulatory mechanism for ensuring ordered and coordinated cell cycle progression. The SCF and APC E3 ligases have been characterized to play pivotal roles in regulating the cell cycle progression by timely degrading various critical cell cycle regulators. This Brief reviews recent studies that have shown that deregulation of signaling pathways in which the two ubiquitin ligases are involved causes aberrant cell cycle regulation, in turn leading to tumorigenesis. The text also discusses how SCF and APC may present promising therapeutic targets to treat various cancers. 124 pp. Englisch.
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Da: Majestic Books, Hounslow, Regno UnitoMajestic Books
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EUR 80,05
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Condizione: New. Print on Demand pp. 126 11 Illus. (Col.).
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Da: Biblios, frankfurt am main, HESSE, GermaniaBiblios
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Condizione: New. PRINT ON DEMAND pp. 126.
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Da: moluna, Greven, Germaniamoluna
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Includes updated profiles of SCF and APC cellular functions and their characterized ubiquitin substratesIntroduces the emergent SCF family members in the human genome and summarizes phenotypes in which the adapter pr…oteins of SCF and APC are manip.
Lingua: Inglese
Editore: Springer, 2021
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: Basi6 International, Irving, TX, U.S.A.Basi6 International
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Condizione: Brand New. New. US edition. Print on demand title. Delivery takes 20-25 days.
Lingua: Inglese
Editore: Springer, 2021
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: Brook Bookstore On Demand, Napoli, NA, ItaliaBrook Bookstore On Demand
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Condizione: new. Questo è un articolo print on demand.
Lingua: Inglese
Editore: Springer, 2020
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: Brook Bookstore On Demand, Napoli, NA, ItaliaBrook Bookstore On Demand
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Condizione: new. Questo è un articolo print on demand.
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Editore: Springer Nature Singapore Jan 2021, 2021
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRL…s, which are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine. 380 pp. Englisch.
Lingua: Inglese
Editore: Springer Nature Singapore Jan 2020, 2020
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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- Print on Demand
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 160,49
EUR 23,00 spedizioneSpedito da Germania a U.S.A.Quantità: 2 disponibili
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, whic…h are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine. 380 pp. Englisch.
Lingua: Inglese
Editore: Springer Singapore, 2021
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: moluna, Greven, Germaniamoluna
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EUR 136,16
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Summarizes all the important aspects of CRLsProvides potential strategies for targeting various human diseasesWritten by pioneers in the field of ubiquitin and neddylationDr. Yi Sun.
Lingua: Inglese
Editore: Springer Singapore, 2020
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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- Print on Demand
Da: moluna, Greven, Germaniamoluna
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EUR 136,16
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Summarizes all the important aspects of CRLsProvides potential strategies for targeting various human diseasesWritten by pioneers in the field of ubiquitin and neddylationDr. Yi Sun.
Lingua: Inglese
Editore: Springer, Springer Jan 2020, 2020
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 160,49
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which ar…e activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 380 pp. Englisch.
Lingua: Inglese
Editore: Springer, Springer Jan 2021, 2021
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 160,49
EUR 60,00 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, w…hich are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 380 pp. Englisch.
Lingua: Inglese
Editore: Springer, 2021
Serie: Advances in Experimental Medicine and Biology, Libro 472 di 544. Libro 472 di 544 - Advances in Experimental Medicine and Biology
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Da: Majestic Books, Hounslow, Regno UnitoMajestic Books
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EUR 228,31
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Condizione: New. Print on Demand.
